51 results
Pathophysiology of Tumor Lysis Syndrome (TLS)
Tumor Cell Lysis
-> Release of DNA
 • Purines -> Hypoxanthine /
Pathophysiology ... of Tumor Lysis Syndrome ... -> Allantoin (High ... #TumorLysis #Syndrome ... #TLS #Pathophysiology
Breast Discharge - Differential Diagnosis Algorithm
High Prolactin + Normal TSH
 • Microprolactinoma
 • Steroid Hormone Intake
Diagnosis Algorithm High ... • Bronchogenic Tumor ... Prolactin + High ... Diagnosis #Algorithm #Endocrinology ... #Causes
Hirsutism & Virilization - Differential Diagnosis Algorithm
ADRENAL EXCESS
Ovarian
 • Polycystic Ovarian Syndrome
 • Hyperthecosis
 • Tumor
Adrenal
Hyperthecosis • Tumor ... • Cushing's Syndrome ... Tumor Low Serum ... Diagnosis #Algorithm #endocrinology ... #causes
Amenorrhea - Differential Diagnosis Algorithm
Elevated FSH
 • Premature Ovarian Failure
 • Menopa use
 • Spontaneous
Bleed With
Polycystic Ovarian Syndrome ... Abnormalities High ... • Empty Sella Syndrome ... Diagnosis #Algorithm #endocrinology ... #causes
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
SAME, Cushing Syndrome ... • HTN, High Aldosterone ... Renin secreting tumor ... , Gitelman syndrom ... Diagnosis #Algorithm #causes
Hypoglycemia Workup and Differential Diagnosis
Workup:
 • Sulfonylurea Labs
 • Anti-lnsulin Ab - Insulin Autoimmune Syndrome
 •
Insulin Autoimmune Syndrome ... with high tumor ... metabolic demand causes ... Insulin Autoimmune Syndrome ... Diagnosis #insulinoma #endocrinology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... immature blasts and high ... WBC count cause ... • Pathophysiology ... Spontaneous if high
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
Diuretics (late) • High ... , Gitelman Syndrome ... hyperaldosteronism • High ... Renin-secreting tumor ... Algorithm #Nephrology #Causes
Causes of Primary Amenorrhea - Differential Diagnosis Algorithm
No onset of menarche by age 16 with secondary
Causes of Primary ... Ovarian Etiology - High ... ) • 45, XO Turner ... Irradiation • Tumor ... Diagnosis #Algorithm #Causes
Causes of Hypercalcemia
Hypercalcemia due to increased bone Ca2+ resorption:
 • Primary hyperparathyroidism, Malignancy, Pseudohyperparathyroidism, Renal failure,
Causes of Hypercalcemia ... calcium)-alkali syndrome ... Hypercalcemia #Causes ... diagnosis #calcium #high ... #endocrinology