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diagnosis syndrome management oncology tumorlysis activetb tb treatment tuberculosis acutekidneyinjury cairoandbishop differential etiology hematology howardcriteria hyperkalemia hyperphosphatemia hyperuricemia hypocalcemia infections
Tumor lysis syndrome (TLS) - Pathophysiology: → Massive tumor cell lysis → Release of large amounts of K+,
Tumor lysis syndrome ... (TLS) - Pathophysiology ... : → Massive tumor ... cell lysis → Release ... #Pathophysiology
Pathophysiology of Tumor Lysis Syndrome (TLS) Tumor Cell Lysis -> Release of DNA • Purines -> Hypoxanthine /
Pathophysiology ... of Tumor Lysis Syndrome ... (TLS) Tumor Cell ... Lysis -> Release ... #Pathophysiology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis vs Tumor ... /- rasburicase Tumor ... : Lysis of tumor ... rate or large tumor ... #Leukostasis #Tumor
Tumor Lysis Syndrome - Workup and Management Initial workup: BMP, Serum uric acid, LDH, Urine output, Consider
Tumor Lysis Syndrome ... Treatment of Clinical ... TLS: • IV fluids ... ICU transfer • Tumor ... #Tumor #Lysis #
Tumor Lysis Syndrome (TLS) Pathophysiology Culprits: ALL, Burkitt, SCLC Cells all die at once = ↑Phos, ↓Ca, ↑K,
Tumor Lysis Syndrome ... (TLS) Pathophysiology ... worsens above #Tumor ... #Lysis #Syndrome ... #TLS #Pathophysiology
Tumor lysis syndrome refers to the constellation of metabolic disturbances that occurs when large numbers of
Tumor lysis syndrome ... acutekidneyinjury #Pathophysiology ... #Presentation #TLS
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS Laboratory TLS: • Uric
Classification of Tumor ... Lysis Syndrome ... (TLS) and Treatment ... Laboratory TLS ... Calcium ≤ 7.0 mg/dL Clinical
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
tuberculosis (LTBI) Pathophysiology ... Recent infection • Pulmonary ... Immunosuppression • Tumor ... • HIV: 2/3 pulmonary ... characteristic features Clinical
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
tuberculosis (LTBI) Pathophysiology ... Recent infection • Pulmonary ... Immunosuppression • Tumor ... • HIV: 2/3 pulmonary ... characteristic features Clinical
Nontuberculous Mycobacteria (NTM) Infections Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
Illnesses: • Pulmonary ... including therapy with tumor ... Disease: Clinical ... Lung Disease: • Clinical ... differential #diagnosis #infectiousdiseases
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