107 results
Tumor lysis syndrome (TLS) - Pathophysiology:
→ Massive tumor cell lysis
→ Release of large amounts of K+,
Tumor lysis syndrome ... (TLS) - Pathophysiology ... : → Massive tumor ... #TumorLysis #syndrome ... #TLS #Pathophysiology
Pathophysiology of Tumor Lysis Syndrome (TLS)
Tumor Cell Lysis
-> Release of DNA
 • Purines -> Hypoxanthine /
Pathophysiology ... of Tumor Lysis Syndrome ... (TLS) Tumor Cell ... #TumorLysis #Syndrome ... #TLS #Pathophysiology
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS
Laboratory TLS:
 • Uric
Classification of Tumor ... Lysis Syndrome ... Laboratory TLS ... #TumorLysis #Syndrome ... #management #oncology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... leukapheresis - TLS ... • Pathophysiology ... #TLS #diagnosis ... #management #hematology
Tumor Lysis Syndrome - Workup and Management

Initial workup: BMP, Serum uric acid, LDH, Urine output, Consider
Tumor Lysis Syndrome ... - Workup and Management ... MatthewHoMD #TLS ... Syndrome #diagnosis ... #management #oncology
Tumor lysis syndrome refers to the constellation of metabolic disturbances that occurs when large numbers of
Tumor lysis syndrome ... acutekidneyinjury #Pathophysiology ... #Presentation #TLS
Inherited Colorectal Cancer (CRS) Syndromes
Adenomatous Polyposis Syndromes:
 • Familial Adenomatous Polyposis (FAP), Attenuated FAP (AFAP), MUTYH
Colorectal Cancer (CRS) Syndromes ... Adenomatous Polyposis Syndromes ... Urinary → Lynch Syndrome ... Tuberous Sclerosis (TS ... #diagnosis #management
Acute Kidney Injury (AKI) - Differential Diagnosis Framework
Pre-Renal:
 • Hypovolemia, Cardiorenal, Distributive Shock, HRS, Hypercalcemia, Renal
Abdominal Compartment Syndrome ... , Medications Intra-Renal ... Protein) • AIN: Medication ... • Obstruction (Tumor ... Neurogenic Bladder (Medication
Tumor Lysis Syndrome (TLS) Pathophysiology
Culprits: ALL, Burkitt, SCLC
Cells all die at once = ↑Phos, ↓Ca, ↑K,
Tumor Lysis Syndrome ... (TLS) Pathophysiology ... worsens above #Tumor ... #Lysis #Syndrome ... #TLS #Pathophysiology
Hirsutism & Virilization - Differential Diagnosis Algorithm
ADRENAL EXCESS
Ovarian
 • Polycystic Ovarian Syndrome
 • Hyperthecosis
 • Tumor
Adrenal
Hyperthecosis • Tumor ... • Cushing's Syndrome ... Tumor Low Serum ... Medications ... HYPERTRICHOSIS Medications