21 results
Tumor lysis syndrome (TLS) - Pathophysiology:
→ Massive tumor cell lysis
→ Release of large amounts of K+,
Tumor lysis syndrome ... (TLS) - Pathophysiology ... cell lysis → Release ... #TumorLysis #syndrome ... #TLS #Pathophysiology
Pathophysiology of Tumor Lysis Syndrome (TLS)
Tumor Cell Lysis
-> Release of DNA
 • Purines -> Hypoxanthine /
Pathophysiology ... of Tumor Lysis Syndrome ... Lysis -> Release ... #TumorLysis #Syndrome ... #TLS #Pathophysiology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Lysis Syndrome ... WBC >100k, + lab signs ... Lysis Syndrome: ... : Lysis of tumor ... #Lysis #Syndrome
Cubital Tunnel Syndrome: Pathogenesis and clinical findings

 • Paresthesia of 5th and medial half of 4th
Cubital Tunnel Syndrome ... CubitalTunnel #Syndrome ... #Diagnosis #pathophysiology ... #signs #symptoms ... #msk
Tumor lysis syndrome refers to the constellation of metabolic disturbances that occurs when large numbers of
Tumor lysis syndrome ... acutekidneyinjury #Pathophysiology
Patellofemoral Syndrome - Pathogenesis and clinical findings
 • Anterior Knee Pain with possible symptoms of 'catching'
Patellofemoral Syndrome ... Patellofemoral #Syndrome ... #pathophysiology ... #diagnosis #signs ... #symptoms #msk
Tumor Lysis Syndrome
An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
Tumor Lysis Syndrome ... Walid Malki, MD, MS ... wandering_er #Tumor ... #Lysis #Syndrome
Tumor Lysis Syndrome (TLS) Pathophysiology
Culprits: ALL, Burkitt, SCLC
Cells all die at once = ↑Phos, ↓Ca, ↑K,
Tumor Lysis Syndrome ... (TLS) Pathophysiology ... worsens above #Tumor ... #Lysis #Syndrome ... #TLS #Pathophysiology
Keratoconus: Pathogenesis and Clinical Findings
Genetics
 • Family history of keratoconus
 • Ehlers-Danlos syndrome
 • Down, Turner,
Ehlers-Danlos syndrome ... • Down, Turner ... , Marfan syndromes ... #Keratoconus #pathophysiology ... #ophthalmology
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
allele of RB1 tumor ... Retinoblastoma Signs ... Retinoblastoma #pathophysiology ... #ophthalmology ... #diagnosis #signs