91 results
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... Dehydration • Symptoms ... changes, stroke symptoms ... Lysis Syndrome: • Pathophysiology ... burden • Symptoms
Clinical features of shock from dehydration in an infant

Decreased level of consciousness 
Sunken fontanelle 
Dry mucous
Clinical features ... Reduced tissue turgor ... PhysicalExam #Signs #Symptoms ... #Dehydration #Peds
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
Pathogenesis and clinical ... gene mutated in all ... Retinoblastoma Signs / Symptoms ... Retinoblastoma #pathophysiology ... diagnosis #signs #symptoms
Aortic Stenosis & Bicuspid Aortic Valve (AS)
 • Introduction & Pathophysiology
 • Classifications
 • Epidemiology
 •
Aortic Valve (AS ... Introduction & Pathophysiology ... Epidemiology • Clinical ... AorticValve #cardiology #peds
Pediatric Parasomnias and Nightmares: Pathogenesis and clinical findings

Parasomnias - Micro-arousal episodes during SWS ->
Intense activation of
Pathogenesis and clinical ... Nightmares #Pediatrics #Peds ... #pathophysiology ... #symptoms #pharmacology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
Risk factors: Critical ... blood donor • Pathophysiology ... : ARDS Berlin Criteria ... ARDS to explain symptoms ... transfusion • Pathophysiology
Osteosarcoma 
Most common primary malignant bone tumor in children 
Most Common Sites of Involvement:
1. Distal femur
malignant bone tumor ... proximal femur Clinical ... injury • Systemic symptoms ... Features #Oncology #Peds
Prader-Willi Syndrome: Pathogenesis and clinical findings
 • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Pathogenesis and clinical ... • Deletion of critical ... Syndrome Signs/Symptoms ... Syndrome #genetics #pathophysiology ... #peds #pediatrics
Major Depressive Disorder (MDD): Pathogenesis and Clinical Findings

Symptoms (included in DSM 5 criteria) - Present during
Pathogenesis and Clinical ... Findings Symptoms ... included in DSM 5 criteria ... MoodDisorders #Diagnosis #Pathophysiology ... #Signs #Symptoms
Graves’ Disease: Pathogenesis and Clinical Findings
B & T lymphocyte mediated autoimmunity attack TSH receptor -> Continuous
Pathogenesis and Clinical ... T lymphocytes also ... etiology Signs/Symptoms ... GravesDisease #pathophysiology ... endocrinology #symptoms