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diagnosis neurology ocular symptoms video iridodonesis iris lysis management slitlamp tumor tumorlysis acutekidneyinjury adies behcet cairoandbishop clinical comatose disease etiology
Tumor lysis syndrome (TLS) - Pathophysiology: → Massive tumor cell lysis → Release of large amounts of K+,
Tumor lysis syndrome ... (TLS) - Pathophysiology ... : → Massive tumor ... #TumorLysis #syndrome ... #TLS #Pathophysiology
Pathophysiology of Tumor Lysis Syndrome (TLS) Tumor Cell Lysis -> Release of DNA • Purines -> Hypoxanthine /
Pathophysiology ... of Tumor Lysis Syndrome ... (TLS) Tumor Cell ... #TumorLysis #Syndrome ... #TLS #Pathophysiology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... WBC >100k, + lab signs ... leukapheresis - TLS ... • Pathophysiology ... #TLS #diagnosis
Tumor lysis syndrome refers to the constellation of metabolic disturbances that occurs when large numbers of
Tumor lysis syndrome ... acutekidneyinjury #Pathophysiology ... #Presentation #TLS
Iridodonesis Physical examination revealed iridodonesis, or “dancing” of the iris, which was elicited by rapid movement of
movement, is a sign ... with Marfan’s syndrome ... Iris #SlitLamp #PhysicalExam ... #Video #Ophthalmology ... #Signs #Ocular
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 Tumor Lysis Syndrome (TLS) Pathophysiology Culprits: ALL, Burkitt, SCLC Cells all die at once = ↑Phos, ↓Ca, ↑K,
Tumor Lysis Syndrome ... (TLS) Pathophysiology ... worsens above #Tumor ... #Lysis #Syndrome ... #TLS #Pathophysiology
Keratoconus: Pathogenesis and Clinical Findings Genetics • Family history of keratoconus • Ehlers-Danlos syndrome • Down, Turner,
Ehlers-Danlos syndrome ... • Down, Turner ... , Marfan syndromes ... #Keratoconus #pathophysiology ... #ophthalmology
Retinoblastoma: Pathogenesis and clinical findings • Sporadic mutation -> One allele of RB1 tumor suppressor gene
allele of RB1 tumor ... Retinoblastoma Signs ... Retinoblastoma #pathophysiology ... #ophthalmology ... #diagnosis #signs
Adie's Pupil What? Unknown nature & benign • Regular and mildly dilated pupil (4-6mm); • Light-near dissociaton;
Holmes-Adie Syndrome ... trauma/orbital tumor ... #Adies #Pupil #PhysicalExam ... #neurology #ophthalmology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Behçet's Syndrome ... tests in Behcet syndrome ... interferon alfa, or tumor ... inhibitors • Uveitis- Ophthalmology ... diagnosis #management #signs
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