55 results
Gastric Neuroendocrine Tumor (NET) Types
Type 1 - Chronic atrophic gastritis and pernicious anaemia
Type 2 - Zollinger
Neuroendocrine Tumor ... Zollinger Ellison syndrome ... Neuroendocrine #Tumor ... Classification #oncology
Acute Kidney Injury (AKI) in Patients with Cancer 

Cancer Related 
• Hypercalcemia 
• Intravenous contrast 
•
nephropathy • Solid tumors ... change disease • Hematologic ... Interleukin-2) • Tumor ... lysis syndrome ... #AKI #Cancer #Oncology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis vs Tumor ... /- rasburicase Tumor ... : Lysis of tumor ... rate or large tumor ... #Leukostasis #Tumor
Tumor lysis syndrome (TLS) - Pathophysiology:
→ Massive tumor cell lysis
→ Release of large amounts of K+,
Tumor lysis syndrome ... (TLS) - Pathophysiology ... : → Massive tumor ... #TumorLysis #syndrome ... #TLS #Pathophysiology
Pathophysiology of Tumor Lysis Syndrome (TLS)
Tumor Cell Lysis
-> Release of DNA
 • Purines -> Hypoxanthine /
Pathophysiology ... of Tumor Lysis Syndrome ... (TLS) Tumor Cell ... #TumorLysis #Syndrome ... #TLS #Pathophysiology
Oncologic Emergencies - Differential Diagnosis Framework

HEMATOLOGIC ONCOLOGIC EMERGENCIES:
Hyperviscosity Syndrome:
 • Spontaneous bleeding
 • Shortness of breath
Diagnosis Framework HEMATOLOGIC ... Hyperviscosity Syndrome ... Superior Vena Cava Syndrome ... EMERGENCIES: Tumor ... Lysis Syndrome:
Tumor markers in clinical practice
Colorectal - CEA
Hepatocellular - AFP
Pancreatic - CA 19-9
Ovarian - CA 125
Breast -
Tumor markers in ... clinical practice ... thyroglobulin #Tumor ... laboratory #diagnosis #oncology
Tumor Lysis Syndrome - Workup and Management

Initial workup: BMP, Serum uric acid, LDH, Urine output, Consider
Tumor Lysis Syndrome ... Treatment of Clinical ... ICU transfer • Tumor ... MatthewHoMD #TLS #Tumor ... diagnosis #management #oncology
Tumor Lysis Syndrome (TLS) Pathophysiology
Culprits: ALL, Burkitt, SCLC
Cells all die at once = ↑Phos, ↓Ca, ↑K,
Tumor Lysis Syndrome ... (TLS) Pathophysiology ... worsens above #Tumor ... #Lysis #Syndrome ... #oncology
Risk factor for VTE in cancer patients

Tumor type 

• Very high risk: gastric, pancreas, brain 

•
cancer patients Tumor ... High risk: lung, hematologic ... #VTE #cancer #oncology