22 results
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS
Laboratory TLS:
 • Uric
Classification of Tumor ... Lysis Syndrome ... (TLS) and Treatment ... Calcium ≤ 7.0 mg/dL Clinical ... #management #oncology
Tumor Lysis Syndrome - Workup and Management

Initial workup: BMP, Serum uric acid, LDH, Urine output, Consider
Tumor Lysis Syndrome ... - Workup and Management ... of the above Treatment ... of Clinical TLS ... #management #oncology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... • Pathophysiology ... unless worrisome EKG ... #TLS #diagnosis ... #management #hematology
Tumor Lysis Syndrome
An acute, life-threatening condition that appears within 7 days of starting cytotoxic therapies in
Tumor Lysis Syndrome ... with Ca only if EKG ... #Lysis #Syndrome ... #TLS #oncology ... #management #UricAcid
Rhabdomyolysis - Differential Diagnosis and Management Summary

Trauma:
 • Immobilization, Crush iniury, Compartment syndrome, Electrical injury
Exertional:
 •
Diagnosis and Management ... iniury, Compartment syndrome ... HIV, Influenza, TSS ... Dermatomyositis) AKI - Pathophysiology ... per day until stable
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
Summary of Oncologic ... antibiotics TLS ... (tumor-lysis syndrome ... low Ca - q8 h TLS ... interventional radiology
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
Clinical Picture ... Generalized fatigue - ALS ... Serologic and EMG ... Clinical DX: - ... Gravis #diagnosis #management
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Pathophysiology ... Prednisone 5mg/kg ... APML #diagnosis #management ... #hematology #oncology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Demyelinating Syndrome ... Disease, PRES Pathophysiology ... Lumbar Puncture, EEG ... cerebritis #diagnosis #management
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
Diagnosis and Management ... Pathophysiology ... Clinical Manifestations ... Treatment: • ... #treatment #neurology