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differential management cancer hematology nephrology syndrome treatment bells bonetumors causes classification dehydrogenase disease elevated emergencies framework hyperkalemia hyperphosphatemia injury kidney
Acute Kidney Injury (AKI) in Patients with Cancer Cancer Related • Hypercalcemia • Intravenous contrast •
Acute Kidney Injury ... Interleukin-2) • Tumor ... lysis syndrome ... #Cancer #Oncology ... #Differential #Diagnosis
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis vs Tumor ... /- rasburicase Tumor ... of tumor cells ... rate or large tumor ... #Leukostasis #Tumor
Malignant Bone Tumors: Pathogenesis of X-ray appearance • Metastatic bone tumors (aka. cancerous cells from systemic
tumors (aka. cancerous ... Signs/Symptoms: ... and tumor (Ill-defined ... tumor #BoneTumors ... Malignant #Radiology #Diagnosis
Causes of HyperKalemia - Differential Diagnosis Increased extracellular K+: • Tissue injury • Hemolysis • Rhabdomyolysis •
- Differential Diagnosis ... Rhabdomyolysis • Tumor ... lysis syndrome ... glycosides • High acute ... Elimination: • AKI
Workup for Hyperphosphatemia - Differential Diagnosis Framework Rule out spurious hyperphosphatemia: paraproteinemia, hyperlipidemia, hemolysis, hyperbilirubinemia, liposomal amphotericin
- Differential Diagnosis ... t-PA, heparin Acute ... Rhabdomyolysis, Tumor ... lysis syndrome, ... Kidney Disease: • AKI
Oncologic Emergencies - Differential Diagnosis Framework HEMATOLOGIC ONCOLOGIC EMERGENCIES: Hyperviscosity Syndrome: • Spontaneous bleeding • Shortness of breath
- Differential Diagnosis ... of breath • Neurologic ... EMERGENCIES: Tumor ... Lysis Syndrome: ... Hyperuricemia • Acute
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework LDH is a cytoplasmic enzyme present in tissues throughout
- Differential Diagnosis ... throughout the body ... ) • Tumor lysis ... syndrome (large tumor ... associated with any symptoms
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
, APML, CLL Acute ... Fibrinolysis & DIC • Tumor ... lysis syndrome: ... Leukemia #Hematology #Oncology ... #Diagnosis
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
skin injury) • Neurologic ... interferon alfa, or tumor ... inhibitors • Uveitis- Ophthalmology ... #management #signs ... #symptoms #rheumatology
Multiple Sclerosis - Summary Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
Forms of MS: • Tumor-like ... Signs and symptoms ... objective evidence of neurologic ... ) • Acute: ... #management #neurology
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