38 results
Pathophysiology of Tumor Lysis Syndrome (TLS)
Tumor Cell Lysis
-> Release of DNA
 • Purines -> Hypoxanthine /
Pathophysiology ... of Tumor Lysis Syndrome ... (TLS) Tumor Cell ... urine pH) • Hypocalcemia ... • Hyperkalemia
Causes of HyperKalemia - Differential Diagnosis
Increased extracellular K+:
 • Tissue injury
 • Hemolysis
 • Rhabdomyolysis
 •
Causes of HyperKalemia ... Rhabdomyolysis • Tumor ... Elimination: • AKI • Hypovolemia ... blockers - MCW Nephrology ... MCW_Nephrology #HyperKalemia
Adrenal Incidentalomas: Hormone Evaluation
 • Zona Glomerulosa: Primary Hyperaldosteronism?
    - Aldosterone and renin
Aldosterone and renin if hypokalemia ... for those with tumor ... mendesthiagob #Adrenal #Tumors ... Diagnosis #workup #endocrinology
Tumor lysis syndrome refers to the constellation of metabolic disturbances that occurs when large numbers of
Tumor lysis syndrome ... hyperuricemia, #hyperkalemia ... hyperphosphatemia, #hypocalcemia ... acutekidneyinjury #Pathophysiology
Hypokalemia Differential Algorithm
Acidosis
 - RTA
 - Diarrhea
pH Normal 
 1. Decreased Mg 
 2. Intracellular Shift
Hypokalemia Differential ... Renin secreting tumor ... NephTwitter) #Hypokalemia ... Causes #Workup #Nephrology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis vs Tumor ... /- rasburicase Tumor ... : Lysis of tumor ... rate or large tumor ... #Leukostasis #Tumor
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Hypokalemia - Differential ... Renin secreting tumor ... @priti899 #Hypokalemia ... potassium #low #nephrology
Causes of Hypokalemia - Differential Diagnosis Algorithm
Defining the cause of hypokalemia starts by measuring urinary K
Causes of Hypokalemia ... Defining the cause of hypokalemia ... Hypomagnesemia-induced hypokalemia ... Renin-secreting tumor ... algorithm #causes #nephrology
Hypocalcemia - Differential Diagnosis Algorithm - Low and High PTH
LOW PTH - Hypoparathyroid
 - Congenital (Pediatric)
Hypocalcemia - Differential ... Tumor lysis syndrome ... laxatives) #Hypocalcemia ... Algorithm #PTH #endocrinology
Pituitary Mass Effects - Pathogenesis and Clinical Findings
 • Pituitary turnors are almost always a benign
• Pituitary turnors ... the pituitary tumor ... Signs / Symptoms ... #SideEffects #endocrinology ... mnemonic #GLFTAP #pathophysiology