35 results
Osteoporosis: Pathogenesis and risk factors

 • Age > 30 (post-peak bone mass)
 • Post-menopausal women ->
30 (post-peak bone ... Decr estrogen • Bone ... Corticosteroid use • Primary ... #Osteoporosis #pathophysiology ... #signs #symptoms
Pathologic / Fragility Fractures - Differential Diagnosis Algorithm 
Tumours
 - See Bone Lesions Scheme
Paget's Disease
 -
Diagnosis Algorithm ... Tumours - See Bone ... Phosphate Deficiency Primary ... • Bone Marrow ... Fractures #Pathologic #MSK
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
ALP) Elevation - Differential ... Diagnosis Algorithm ... Most common symptoms ... - Bone symptoms ... - Drugs - Primary
Primary Biliary Cirrhosis - Diagnosis Algorithm
Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort
Signs: Jaundice, Xanthelasmata, Hepatomegaly
Associated history:
Primary Biliary ... Cirrhosis - Diagnosis Algorithm ... Symptoms: Fatigue ... quadrant discomfort Signs ... of autoimmune disease
Diagram of different types of bone tumors that can occur around the knee on XRay -
Diagram of different types ... phase • Paget disease ... blade of grass sign ... #Differential # ... Radiology #XRay #msk
Gaucher Disease 

Pathophsiology
 • Lysosomal storage disorder
 • Deficiency of ß-glucocerebrosidase
• Accumulation of glucosylceramide in macrophages
Diagnosis
Pathophsiology ... Neurological involvement (type ... Osteonecrosis, bone ... #Diagnosis #Signs ... #Symptoms
Hypercalcemia - Differential Diagnosis Algorithm
Primary Hyperparathyroidism
 • Adenoma
 • Hyperplasia
 • MEN 1 and 2A
Tertiary Hyperparathyroidism
Hypercalcemia - Differential ... Diagnosis Algorithm ... Primary Hyperparathyroidism ... Cytokine-Mediated Bone ... #Diagnosis #Algorithm
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
- B symptoms ... translocation • Types ... on: - Cell type ... involvement Differential ... oncology #diagnosis #differential
Diagram of different types of bone tumors that can occur around the knee on XRay
Age <
Diagram of different types ... phase • Paget disease ... blade of grass sign ... #Differential # ... Radiology #XRay #MSK
Vascular Joint Pain - Differential Diagnosis Algorithm 
 - Constant Pain (Ischemia)
 - Acute Onset
 -
Diagnosis Algorithm ... Peripheral Vascular Disease ... fractured long bone ... Vascular #JointPain #MSK ... #Differential #