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rheumatology management erythematosus sle systemic dermatology differential activation arthropathies arthropathy calcium classification cppd deposition disorders macrophage mas monoarthritis monoarticular msk
Joint Disorders - Differential Diagnosis Algorithm Monoarthritis • Septic • Crystalline - Gout
- Differential Diagnosis ... Algorithm Monoarthritis ... arthritis - (Reiter’s syndrome ... with Systemic Lupus ... like “butterfly rash
Skin Conditions Associated with Joint Pain Rash • Human parvovirus B19 infection Malar rash • SLE • Human parvovirus B19 infection •
Associated with Joint ... Pain Rash ... Antiphospholipid-antibody syndrome ... lesions • Discoid lupus ... #differential #diagnosis
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... - Summary Antinuclear ... Treatment: • ... #Systemic #Lupus ... #diagnosis #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... Manifestations: Malar rash ... life-threatening • Treatment ... Evolution: Chronic disease ... #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... Malignancy (e.g. hematologic ... Arthritis: • Joint ... arthropathy • 90% joints ... Erythematosus #Diagnosis
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Photosensitivity, Butterfly rash ... Demyelinating syndromes ... pain (20%) Renal disease ... signs #symptoms #diagnosis ... #rheumatology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
SAPHO Syndrome Summary ... Diagnosis: ... • A clinical diagnosis ... and lower jaw Treatment ... osteoarticular and skin disease
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
• Systemic lupus ... Petechial or purpuric rash ... Treatment: • Corticosteroids ... #Diagnosis #Management ... #Hematology #Rheumatology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
with systemic disease ... , breast CA - Hematologic ... - Lupus - Leukemia ... Treatment: - Systemic ... #diagnosis #dermatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
inflammation Others: • Lupus ... vesicular eruption - Joints ... mucositis - Rash ... such as systemic lupus ... #rheumatology #
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