23 results
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
- Differential Diagnosis ... for workup, including ... Rebound effect from treatment ... Vasculitides, IBD, Celiac disease ... #Algorithm #hematology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Clinical triad ... arthritis, Skin rash ... Differential Diaqnoses ... #diagnosis #management ... #treatment #rheumatology
Secondary Syphilis Rash
Secondary syphilis is the most contagious of all the stages of this disease, and
stages of this disease ... with or without treatment ... , but without treatment ... #Diagnosis #Clinical ... #Photo #Dermatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
40, F:M 9:1 • Clinical ... Manifestations: Malar rash ... • Immunologic Workup ... life-threatening • Treatment ... Evolution: Chronic disease
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... NPSLE rare, Malar rash ... • Immunologic Workup ... Evolution: Chronic disease ... #diagnosis #management
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
IgG4-Related Disease ... Clinical history ... IgG4 #Related #Disease ... #phenotypes #workup ... #treatment #rheumatology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
minimal tumor burden Diagnosis ... immunophenotype Clinical ... chemotherapy for low-risk disease ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
with systemic disease ... - Rash: multiple ... , breast CA - Hematologic ... Treatment: - Systemic ... #dermatology #oncology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... cells can indicate disease ... microglobulin Treatment ... #workup #oncology ... #hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Fever is the main clinical ... Petechial or purpuric rash ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis ... #Management #Hematology