11 results
Validation of the Step-By-Step Approach to Febrile Infants

#Diagnosis #Management #Pediatrics #Peds #Febrile #Infant #StepByStep #Algorithm #LP
Febrile Infants #Diagnosis ... #Management #Pediatrics ... #Peds #Febrile ... #LP #Antibiotics ... Stratification #Fever
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Script Signs and symptoms ... (transfusions, antibiotics ... if neutropenic fever ... #management #treatment ... #hematology
“Step by Step” – the new kid on the block – aims to risk stratify this
an infant with fever ... CRP < 20 mg/L #Diagnosis ... #Management #Pediatrics ... #Peds #Febrile ... #LP #Antibiotics
The Febrile Infant Step-by-Step Algorithm
This is an algorithm developed by European emergency physicians to identify low-risk
92.0% and 46.9% #Diagnosis ... #EBM #Management ... #Pediatrics #Peds ... #LP #Antibiotics ... Stratification #Fever
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
HLH signs and symptoms ... following: • Fever ... rapidly, and empiric antibiotic ... #management #treatment ... #hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Subacute-Acute: • Common: fever ... Imaging: CXR- pulmonary ... opacities • Diagnosis ... : >3 symptoms, or ... #management #hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Presentation: • Fever ... - β-lactam antibiotics ... • Improve the symptoms ... Anemia #oncology #hematology ... #diagnosis #management
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
: - Fever + ANC ... 500 → may stop antibiotics ... syndrome): - Hematologic ... renal failure, pulmonary ... Oncology #HemeOnc #Diagnosis
Cryptogenic Organizing Pneumonia - Illness Script

PATHOPHYSIOLOGY: Unknown trigger, reversible inflammatory/fibroproliferative process. Polypoid fibroblastic aggregates that plug
Females SIGNS/SYMPTOMS ... misdiagnosed as CAP • Symptoms ... Cough, dyspnea, fever ... identified (autoimmune, meds ... #management #pulmonary
Preoperative Risk Evaluation

Major Pre-Op Questions:
1. Does the patient have any modifiable risk factors that could be
or family - Ever ... murmur 3/6) - Pulmonary ... event, follow ACC algorithm ... medical and surgical management ... stratification #diagnosis