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differential rheumatology treatment cancer disease mgus acute aki anemia aplastic behcet capillary cerebritis clarksons classification clinical cns emergencies erythematosus gammopathies
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis Neurologic-Centered: (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
- Differential Diagnosis ... Neurologic-Centered ... capillary leak syndrome ... • Schnitzler syndrome ... #hematology #oncology
Multiple Myeloma and Monoclonal Gammopathies C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN R
Causes of false- ... amyloidosis Other causes ... plasmacytoma, POEMs syndrome ... Gammopathies #MGUS #diagnosis ... #hematology #oncology
Acute Kidney Injury (AKI) in Patients with Cancer Cancer Related • Hypercalcemia • Intravenous contrast •
tubulopathy • Monoclonal ... change disease • Hematologic ... #AKI #Cancer #Oncology ... #Differential #Diagnosis ... Classification #Nephrology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... and Management ... old, ~10,000 new cases ... Myelodysplastic #Syndrome ... #hematology #oncology
Oncologic Emergencies - Differential Diagnosis Framework HEMATOLOGIC ONCOLOGIC EMERGENCIES: Hyperviscosity Syndrome: • Spontaneous bleeding • Shortness of breath
- Differential Diagnosis ... Framework HEMATOLOGIC ... Hyperviscosity Syndrome ... of breath • Neurologic ... #differential #diagnosis
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Can Feature A Monoclonal ... et diutinum Neurologic ... Amyloidosis and monoclonal ... Paraproteinemias #Hematology ... #Diagnosis #Oncology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... autoantibodies that will cause ... Erythematosus #SLE #CNS #neurology ... #rheumatology # ... #management #treatment
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
skin injury) • Neurologic ... ) Differential Diagnosis ... refractory disease : monoclonal ... #diagnosis #management ... signs #symptoms #rheumatology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... and petechiae Causes ... Aplastic #Anemia #oncology ... #hematology #diagnosis ... #management
Clarkson’s Disease - Capillary leak syndrome Epidemiology: Roughly 150 published cases, Median age 50 years, No sex
Capillary leak syndrome ... 150 published cases ... Monoclonal gammopathy ... #diagnosis #management ... timeline #treatment #rheumatology
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