19 results
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
response -> Subacute cutaneous ... lesions and plaques ... hair follicles -> causes ... inflammation on skin ... #signs #symptoms
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Sjögrens (15%) Skin ... Photosensitivity, Butterfly rash ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
NPSLE rare, Malar rash ... Rare (SSA+ for cutaneous ... #sle #comparison ... #table #rheumatology ... #diagnosis #management
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
- Rash: multiple ... Most common extra cutaneous ... Episcleritis Signs ... Causes: - Idiopathic ... ’s syndrome - Lupus
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Diagnosis Algorithm ... reddish-purple lesions ... Autoimmune Vasculitis (lupus ... cryoglobulins • Skin
Papulosquamous Skin Rash - Differential Diagnosis Algorithm
Erythrematous or violaceous papules & plaques with overlying scale
 •
Papulosquamous Skin ... Rash - Differential ... Auspitz sign, Koebner's ... soles • Discoid Lupus ... #Algorithm #causes
Clinical Characteristics of Simple vs Complex Cutaneous Leishmaniasis 
Simple CL
 - Caused by a Leishmania species
Simple vs Complex Cutaneous ... Simple CL - Caused ... ) Complex CL: Caused ... Leishmaniasis #diagnosis ... #comparison #table
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... papulosquamous lesions ... Differential Diagnosis ... Malignancy (e.g. hematologic ... Seizures • Strokes Skin
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
DERMATOMYOSITIS Cutaneous ... (blue-purple) rash ... • Erythematous rash ... lesions: antihelix ... #dermatology #diagnosis
Pigmented Purpuric Dermatoses (PPD) - Capillaritis

Group of chronic, benign, cutaneous eruptions characterized by the presence of
chronic, benign, cutaneous ... - This iron causes ... brown tint of the rash ... #differential #diagnosis ... #dermatology