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differential nephrology potassium hypokalemia algorithm management treatment workup binders binding criticalcare crystalloids disorders diuresis diuretics drugs effects endocarditis enteral excretion
Potassium-Binding Agents to Treat Hyperkalemia Sodium zirconium cyclosilicate (Lokelma): • Mechanism: Preferentially captures K in exchange for
constipation, diarrhea, nausea ... ); nausea, vomiting ... patients sensitive to high ... #medications #pharmacology ... #table #comparison
Causes of HyperKalemia - Differential Diagnosis Increased extracellular K+: • Tissue injury • Hemolysis • Rhabdomyolysis •
Causes of HyperKalemia ... - Differential Diagnosis ... glycosides • High ... blockers - MCW Nephrology ... #Causes
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Diagnosis Framework ... phlebotomy High ... Medications 2. ... #causes #potassium ... #high #nephrology
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Diagnosis Framework ... phlebotomy High ... Medications 2. ... #causes #potassium ... #high #nephrology
Hypokalemia Evaluation Algorithm Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
wasting from other causes ... suggests extra-renal causes ... urinary losses: • High ... #diagnosis #Algorithm ... differential #potassium #nephrology
Causes of Hyperkalemia - Differential Diagnosis Framework • Cellular Shift: - Exercise
Causes of Hyperkalemia ... hyperosmolality - Medications ... to Aldosterone: K ... Leukocytosis UCSD ... #high
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Hyperkalemia - Diagnosis ... Etiology: • Medications ... only if no clear cause ... Elimination (see Table ... STOP offending medications
Drugs associated with hypokalemia and hypomagnesemia Hypokalemia - Shift from extracellular fluid to intracellular fluid compartment -
associated with hypokalemia ... - Insulin (high ... hypomagnesemia #Medications ... #differential #diagnosis ... #nephrology #Causes
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential Diagnosis ... family history - Medications ... , decrease vit K) ... (CVID, WAS), (neurologic ... psychiatric changes), high
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
Loop Diuretics; High-Ceiling ... Hyponatremia • Hypercalcemia ... Kidney stones caused ... #Pharmacology # ... Medications #Table
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