19 results
Blood Culture-Negative Infective Endocarditis (BCNIE)
Definition: No etiology found after 3 separate blood cultures remain negative for
antimicrobials, clinical ... but important causes ... BCNIE Diagnostic ... See charts - ... #differential #
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Platelet Disorders - Differential ... Diagnosis and Workup ... test, ANA (e.g., SLE ... #Diagnosis #Causes ... #Workup #hematology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
) - Diagnosis and ... 40, F:M 9:1 • Clinical ... • Immunologic Workup ... Positive in 60-80% of cases ... Erythematosus #Diagnosis
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... • Immunologic Workup ... 40, F:M 9:1 • Clinical ... • Immunologic Workup ... #diagnosis #management
Major neurocognitive disorders (MNCD): Diagnosis and workup 

1) Clinical diagnosis Cognitive impairment + loss of autonomy
2)
1) Clinical diagnosis ... Alzheimer - 1st cause ... Dementia - 2nd cause ... MNCD #Dementia #Differential ... #Diagnosis #Geriatrics
Top 10 situations when to think about lupus
1) Inflammatory joint pain (especially in the wrists and
the face (many differential ... diagnoses, including ... including in children (pediatric ... SLE) 10) When ... #sle #clues #system
Dermatological semiology of Cutaneous Vasculitis 

Clinicopathologic correlations
 • Purpura, papules, pustules, necrosis: involvement of small vessels
Identification of causes ... disease (10%) : SLE ... signs #lesions #diagnosis ... #clinical #manifestations ... pathology #lesions #differential
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... ) Clinical Manifestations ... Disease, PRES Pathophysiology ... autoantibodies that will cause ... Erythematosus #SLE
Polycythemia - Differential Diagnosis Algorithm
Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Polycythemia - Differential ... Better call hematology ... some time, let’s see ... you’ll do a good workup ... #workup #hematology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... = nonspecific (nausea ... infiltration) Differential ... Diagnosis: Viral ... Maternal Support - Critical