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diagnosis hepatology management algorithm ultrasound causes criticalcare gastroenterology lfts hepatic nephrology obstetrics radiology transaminitis workup appearance bariatric clinical comparison complications
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury Hepatocellular Liver Injury • AST/ALT elevation
Liver Enzymes (LFTs ... and Cholestatic Liver ... value = (ALT + ULN ... phosphatase + ULN ... Transaminitis #diagnosis #differential
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... - Differential ... Severe ALT > 15x ULN ... Mild ALT < 5x ULN ... #LiverEnzymes #Differential
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Tests - Differential ... Severe - ALT >15X ULN ... Moderate - ALT 5-15X ULN ... Mild - ALT < 5x ULN
The Gastroenterology Consult Primer Guide to Calling a GI Consult HPI: - Start with reason for consult
consult - I-liner ... lipase PMH: - Focus ... on prior GI/Liver ... last meal - Treatment ... GregoryTBrennan #Liver
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Liver Chemistries ... R-value: Serum (ALT/ULN ... ALT) / (Alk phos/ULN ... Identify Acute Liver ... chemistry #diagnosis #differential
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... hepatocytes → Liver ... malaise) → Acute liver ... AST/ALT (5-10x ULN ... infiltration) Differential
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
disease to acute liver ... hepatocellular pattern of liver ... ALT + AST > 5x ULN ... AND IgG > 2x ULN ... regarding need for treatment
Hepatitis B - Treatment Indications Treatment not indicated: • Immune tolerant state - HBe-Ag detectable, high HBV
Hepatitis B - Treatment ... Indications Treatment ... IU/mL and ALT > ULN ... infection with severe liver ... mg/dL) or acute liver
Hepatobiliary Manifestations of Sickle Cell Disease Acute sickle cell hepatic crisis: • Fever, acute onset RUQ pain,
Supportive with treatment ... progressing to acute liver ... Liver transplant ... hepatology #hepatitis #differential
Shock - Differential Diagnosis Framework - MAP <65. SBP <90, drop in SBP > 40 -
Shock - Differential ... Insufficiency, Liver ... Dehydration Shock Treatment ... Sophia_Hayes_MD #Shock #Differential ... criticalcare #algorithm #treatment
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