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Liver Function Test (LFTs) Elevation AST - Cardiac and skeletal muscle, kidney, brain ALT - More specific for
Function Test (LFTs ... Phosphatase, ALT ≥ 3x ULN ... Value = (ALT / ULN ... ALT) / (ALP / ULN ... #FunctionTest #LFTs
Bilateral LMN palsy with tongue weakness, wasting and fasciculations. → Bulbar motor Neuron disease Note
Bilateral LMN palsy ... differentiates this from an UMN ... fasciculations #LMN ... #CNXII #CN12 #clinical
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 Upper Motor Neuron (UMN) lesions are lesions occurring anywhere in the CNS from the brain up
Motor Neuron (UMN ... However, in UMN ... clinically characterized ... very different clinical ... @DharSaty #UMN
Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
combination of the clinical ... cellular function Clinical ... involving both UMN ... Exam: clinical evidence ... of both UMN and
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury Hepatocellular Liver Injury • AST/ALT elevation
Liver Enzymes (LFTs ... value = (ALT + ULN ... phosphatase + ULN ... Liver #Enzymes #LFTs
Incomplete spinal cord syndromes (ISCS) • Central - Small Lesion - Suspended sensory deficit, classic cape
Disproportionate motor (UMN ... Ipsilateral weakness (UMN ... small band of LMN ... paraparesis (mixed UMN ... and LMN types)
An Approach to Jaundice Workup Algorithm by CBC and LFT Pattern - Dr. Eric Strong @DrEricStrong #Jaundice #Workup
Algorithm by CBC and LFT ... Algorithm #Patterns #LFTs
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Severe ALT > 15x ULN ... Moderate ALT 5-15x ULN ... Mild ALT < 5x ULN ... • Others #LFTs
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Severe - ALT >15X ULN ... Moderate - ALT 5-15X ULN ... Mild - ALT < 5x ULN ... Burak @kwburak #LFTs
Generalized Weakness - Differential Diagnosis Framework "l feel weak": • Infectious: Influenza, EBV, PNA, Bacteremia, Sepsis •
Rhabdomyolysis, Critical ... Infection • Neuro: UMN ... stroke, tumor), LMN
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