1616 results
Causes of Hyponatremia - Differential Diagnosis Algorithm
Hypovolemia, UNa > 20: 
 • Renal losses, Diuretic excess,
Hypovolemia, UNa ... Hypovolemia, UNa ... Hypervolemia, UNa ... Hypervolemia, UNa ... Algorithm #Causes #nephrology
Hyponatremia Diagnosis Algorithm
UOsm ≥ POsm - Vasopressin-Dependent
 • UNa < 20 mEq/L - Appropriate (↓ EABV)
Vasopressin-Dependent • UNa ... Cirrhosis • UNa ... algorithm #causes #nephrology
Modified Hyponatremia Algorithm
Hypertonic Hyponatremia: Hyperglycemia, Mannitol, Urologic irrigants
Hypotonic Hyponatremia: 
 • ADH ON (UOsm > 100):
- RAAS ON (UNa ... - RAAS OFF (UNa ... diagnosis #sodium #nephrology
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
algorithm Urine Na ... +K / serum Na >1 ... or Ineffective (UNa ... solute intake, UNa ... table #sodium #nephrology
Visualizing Hypotonic Hyponatremia

 • UNa reveals RAAS activity.
 • UOsm reveals ADH activity.
 • ADH secretion
Hyponatremia • UNa ... Hyponatremia #Graph #nephrology
Management of SIADH
Treat underlying cause:
 • Causes can include pain, primary lung pathology, post-operative phenomenon, medications,
• With lower Na ... osmolality < 538 AND UNa ... #hyponatremia #nephrology
Hyponatremia Differential Diagnosis Algorithm in Cancer
UOsm ≥ 100 mOsm/kg = Urine is inappropriately concentrated for hypotonic
Vasopressin-dependent - UNa ... following HSCT) - UNa ... Cancer #algorithm #nephrology
SIADH Treatment Options
1. Treat underlying cause of SIADH: Pain, Primary lung pathology, Post-operative phenomenon, Medications, Basically
• With lower Na ... osmolality < 538 AND UNa ... Re-check the serum Na ... #hyponatremia #nephrology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
volume (↓distal Na ... ± Urine Lytes: UNa ... suggests ↓ distal Na ... delay HD - Na-Zirconium ... Treatment #potassium #nephrology
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
• Lupus (SLE): ANA ... double-stranded DNA ... Anti-centromere, Scl-70 (DNA ... topoisomerase I), RNA