1361 results
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
• Lupus (SLE): ANA ... double-stranded DNA ... Anti-centromere, Scl-70 (DNA ... topoisomerase I), RNA
Causes of Hyponatremia - Differential Diagnosis Algorithm
Hypovolemia, UNa > 20: 
 • Renal losses, Diuretic excess,
Hypovolemia, UNa ... Hypovolemia, UNa ... Trauma Euvolemia, UNa ... Hypervolemia, UNa ... Hypervolemia, UNa
Rifamycins - Antibiotics Class Overview

Include Rifampin, Rifaximin, Rifapentine, Rifabutin.

Mechanism: Inhibits bacterial DNA-dependent RNA polymerase (unique mechanism).
Inhibits bacterial DNA-dependent ... RNA polymerase
Non-Resolving Pneumonias: Etiologies
Unusual Infections:
 - Immunocompromised patients (e.g.: Mycobacterium, Aspergillosis, Nocardia)
 - Endemic Fungi (e.g.: Histoplasmosis,
- Eosinophilic PNA ... Cryptogenic organizing PNA ... Others: - Pulmonary ... abnormalities (Pulmonary ... Pneumonia #diagnosis #pulmonary
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
algorithm Urine Na ... +K / serum Na >1 ... or Ineffective (UNa ... solute intake, UNa
High-Res Chest CT Patterns - Differential Diagnosis Framework
Reticular:
 • Septal Thickening: Lymphangitic Carcinoma, Interstitial Edema, Alveolar
Hypersensitivity, Acute Eos PNA ... COP, Chronic Eos PNA ... Lymphocytic Int PNA ... Honeycombing: Idiopathic Pulmonary ... Differential #Diagnosis #pulmonary
Hyponatremia Diagnosis Algorithm
UOsm ≥ POsm - Vasopressin-Dependent
 • UNa < 20 mEq/L - Appropriate (↓ EABV)
Vasopressin-Dependent • UNa ... Cirrhosis • UNa
Hemoptysis - Differential Diagnosis Framework
Airways: 
 • Bronchitis
 • Bronchiectasis
 • Malignancy: Primary bronchogenic CA, Endobronchial
Paragonimus westermani, PNA ... syndrome, Idiopathic pulmonary ... Differential #Diagnosis #pulmonary
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Vasculits: ANCA, ANA ... Anti-GBM, Anti-ds-DNA ... , C3/C4, ENA, immunoglobulins
Systemic Sclerosis Associated Autoantibodies
Anti-topoisomerase I (anti-Sc170): Diffuse skin disease, Pulmonary fibrosis
Anti-centromere: Limited skin disease (~93-95%), Pulmonary
skin disease, Pulmonary ... disease (~93-95%), Pulmonary ... Cirrhosis Anti-RNA