12 results
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... - Summary Antinuclear ... severe disease Treatment ... #Systemic #Lupus ... #rheumatology #
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
and Management Summary ... Positive in 60-80% of cases ... life-threatening • Treatment ... Diagnosis #Management #Summary ... #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... autoantibodies that will cause ... Puncture, EEG Treatment ... Erythematosus #SLE ... CNS #neurology #rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
vs SLE Drug Induced ... constitutional symptoms • Treatment ... Discontinuation of causal ... life-threatening • Treatment ... #table #rheumatology
Major Clinical Trials and Evidence Summary for Transfusion Thresholds in Critical Care

TRICC - NEJM 1999 -
Trials and Evidence Summary ... NEJM 1999 - ICU FOCUS ... Blood saves lives ... unnecessary and cause ... Transfusion #Thresholds #Hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Autoimmune diseases: SLE ... Drugs, Unknown cause ... Treatment: • ... diagnosis #management #treatment ... #summary #rheumatology
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Cryoglobulinemia Summary ... • They can cause ... Cryoglobulins Cause ... (e.g. systemic lupus ... classification #rheumatology
COVID-19 - A Seattle Intensivist's One-Page Cheat-Sheet on COVID-19 v2.7 Updated March 26 2020

(v2.7) incorporating newer
as data on new treatment ... 31 • First US case ... dyspnea • 15% URI ... unilateral* • POCUS ... Diagnosis #Management #Summary
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
SAPHO Syndrome Summary ... inflammation of the bones ... Rule out other causes ... and lower jaw Treatment ... SAPHO #Syndrome #Rheumatology
Drug Induced Lupus (DIL)
 • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
is rare in DIL, SCLE-DIL ... constitutional symptoms • Treatment ... Discontinuation of causal ... #DIL #rheumatology ... #diagnosis #treatment