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differential management erythematosus pediatrics sle systemic antiphospholipid apls cerebritis classification cns elevation endocrinology failuretothrive ftt hematology hypercoagulable lactate lactic neurology
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
block • Sjogren syndrome ... polymyositis overlap syndrome ... severe disease Treatment ... #SLE #Summary #diagnosis ... #rheumatology #
Short Stature - Differential Diagnosis Algorithm Normal Variant, Normal Puberty Onset (BA = CA) • Familial Short
21 • Noonan Syndrome ... • Prader-Willi Syndrome ... Russell-Silver Syndrome ... • Turner Syndrome ... Chronic UTI) •
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... autoantibodies that will cause ... permeability Diagnosis ... CNS #neurology #rheumatology ... #cerebritis #diagnosis
Causes of Failure to Thrive - Differential Diagnosis Algorithm Adequate Calorie Consumption - Increased Losses:
Causes of Failure ... Renal Tubular Acidosis ... Disorders • Syndromes ... #Algorithm #Causes ... #Peds #Pediatrics
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
- Differential Diagnosis ... / hypoxemia -> focus ... perfusion - shock->treatments ... before beginning treatment ... - Compartment syndrome
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... SLE • Mikulicz syndrome ... enlargement Sjogren's Syndrome ... #Sjogrens #Syndrome ... #Rheumatology #
Antiphospholipid Syndrome (APLS) Testing - Hypercoagulable Workup Algorithm INDICATIONS FOR TESTING: • Vascular thrombosis
Antiphospholipid Syndrome ... maternal chromosomal causes ... excluded Testing: • Lupus ... Antiphospholipid #Syndrome ... #diagnosis #hematology
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