10 results
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
block • Sjogren syndrome ... Anti-UI-ribonucleoprotein ... polymyositis overlap syndrome ... severe disease Treatment ... Summary #diagnosis #rheumatology
Short Stature - Differential Diagnosis Algorithm
Normal Variant, Normal Puberty Onset (BA = CA)
 • Familial Short
• Turner Syndrome ... Panhypopituitarism Treatment ... Chronic UTI) • ... endocrinology #causes ... #pediatrics
Behcet's Syndrome - Treatment
Ulcers:
 • Treatment: Topical steroids
 • Prevention: Colchicine
 • Azathioprine for refractory disease
Arthritis:
Behcet's Syndrome ... - Treatment Ulcers ... : • Treatment: ... Behcets #disease #Syndrome ... #pharmacology #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... Demyelinating Syndrome ... autoantibodies that will cause ... Erythematosus #SLE ... CNS #neurology #rheumatology
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
thyroid, Sjogren syndrome ... rheumatoid arthritis, SLE ... muscles: “myasthenic crises ... Myasthenia Crises ... immunosuppressants - Meds
Croup Diagnosis and Management Pearls
Common childhood illness, usually viral and self limiting. Characterised by a seal-like
Often an URTI like ... intercostal recession, see-saw ... Treatment: Single ... Diagnosis #Management #pediatrics ... #peds
Causes of Purpura or Easy Bruising in Children

Platelet count reduced, i.e. thrombocytopenia
 - Increased platelet destruction
Causes of Purpura ... thrombocytopenia) - SLE ... Henoch—Schönlein purpura, SLE ... Purpura #Bruising #Causes ... #peds #pediatrics
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
again we might see ... / hypoxemia -> focus ... perfusion - shock->treatments ... before beginning treatment ... - Compartment syndrome
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... overlaps with RA, SLE ... Hypocomplementemia • Can cause ... Adenocarcinoma Treatment ... #Rheumatology #
Relapsing Polychondritis

What is it?
Recurrent inflammation of the cartilage in the body (Autoimmune disorder)

Who?
• Most frequently: 40
hearing loss, nausea ... diseases 30% of cases ... such as: • SLE ... affected tissue Treatment ... Polychondritis #rheumatology