53 results
differential hematology infectiousdiseases oncology neurology rheumatology lung pulmonary summary algorithm microbiology pediatrics barre chronic classification clinical cll dermatology disease guillain
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... old, ~10,000 new cases ... cytopenias (usually anemia ... risk-stratification • Risks: infection ... #Management #treatment
Causes of Depressed / Lethargic Newborn - Differential Diagnosis Algorithm Maternal Related: • Drugs (Ex. SSRI) •
Causes of Depressed ... Malformation • TORCH Infection ... Respiratory Distress Syndrome ... Sepsis Other: • Anemia ... #Peds #Pediatrics
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... Artifact (redo CBC ... Myelofibrosis Infectious ... effect following treatment ... Iron deficiency anemia
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... Idiopathic • Infections ... Treatment: ... oncology #hematology #diagnosis ... #management
Short Stature - Differential Diagnosis Algorithm Normal Variant, Normal Puberty Onset (BA = CA) • Familial Short
- Differential Diagnosis ... Panhypopituitarism Treatment ... CRF) • Infection ... Chronic UTI) • ... endocrinology #causes
Acute Retroviral Syndrome Acute Retroviral Syndrome is the symptomatic presentation of acute human immunodeficiency virus infection •
14%), in which case ... enzymes ↑ • Mild anemia ... Viral hepatitis Diagnosis ... antibody test) Treatment ... #HIV #diagnosis
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
→Activation of CD8 ... Auto-amplification loop Diagnosis ... Drugs, Unknown cause ... Treatment: • ... #management #treatment
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
autoimmune hemolytic anemia ... DDX - Other causes ... : • Nephrotic syndrome ... (Epstein-Barr syndrome ... #management
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... skin that are caused ... petechiae) • Frequent infections ... • Parvovirus infection ... #diagnosis #hematology
Hantavirus Pathogen: Hantavirus - Rodents are the primary reservoir Transmission: • Shed in the urine, feces, saliva of
common route of infection ... Cardiopulmonary Syndrome ... +/- diarrhea Diagnosis ... • Autopsy PCR Treatment ... #management #treatment
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