2753 results
Systemic Lupus Erythematosus (SLE): Pathogenesis

 • Genetic factors (Mutations in HLA- DR2/HLA-DR3 genes, complement genes, cytokine
Erythematosus (SLE ... Environmental factors: UV-light ... (UV-A, UV-B); Viruses ... Erythematosus #SLE
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... Discoid Rash • UV ... Phenomenon #Lupus #SLE
Melanoma Pathogenesis

Environmental exposure (UV light) + genetic susceptibility (CDKN2A, CDK4, MC1R, BRAF, p16/ARF genes) → accumulation
Environmental exposure (UV
Ascites, pericardial effusion, and left pleural effusion on subcostal 4-chamber POCUS echocardiogram

Subcostal window in SLE patient.
subcostal 4-chamber POCUS ... Subcostal window in SLE ... effusion #s4c #POCUS ... echocardiogram #POCUS
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
Highly specific for SLE ... Anti-Ribo-P 5-15% If SLE ... Associated with SLE-SSc-AlM ... higly specific for SLE ... patients with typical SLE
Clinical Manifestations of Systemic Lupus Erythematosus (SLE)

#Systemic #Lupus #Erythematosus #SLE #Manifestations #Signs #Symptoms #Rheumatology #Diagnosis
Erythematosus (SLE ... Erythematosus #SLE
Papillary Muscle Rupture on POCUS

See the "cracking whip"?  This is what papillary muscle rupture looks
Muscle Rupture on POCUS ... See the "cracking ... Echocardiogram #POCUS
Retinal detachment on Ocular POCUS

Patient: "I see floaters"
Me: "I see your problem" 

Dx - retinal detachment
Eric
detachment on Ocular POCUS ... Patient: "I see ... floaters" Me: "I see ... Ophthalmology #POCUS
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Spondyloarthropathies, SLE ... retinal exudates) - SLE ... nodules - RA, SLE ... disease - RA - SLE ... • Seizures - SLE
Intubation Confirmation on POCUS

See the round, shadowing structures?
1. ET Tube in Trachea
2. NG Tube in Esophagus

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Confirmation on POCUS ... See the round ... #Confirmation #POCUS