9 results
REBEL Review 79: Treatment of Hemophilia 

Walkina Out of Pt Room, You Should Know... 
1. Type
REBEL Review 79: Treatment ... of Hemophilia ... of Pt Room, You Should ... #hematology #management ... #treatment #dosing
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
type (e.g. ... possible, patients should ... treatment center ... athletic regimens should ... #hematology
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
von Willebrand Syndrome ... Lymphoproliferative disorders (e.g ... vonWillebrand #Syndrome ... Diagnosis #Management #treatment ... #hematology #differential
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Prednisone 5mg/kg ... initiation • Differential ... diagnosis #management #hematology
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
GI - Felty syndrome ... disease, Vasculitis (e.g ... Boutonnière and swan-neck ... #joint #pain #differential ... #diagnosis #rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... Non-autoimmune rheumatologic ... . hematologic) ... Joint pain • Swan neck ... Erythematosus #Diagnosis #Rheumatology
Causes of Neutropenia - Differential Diagnosis
Neonate:
 - Infection - by far the most common cause
 -
Neutropenia - Differential ... hypertension and/or drug treatment ... Constitutional disorders, eg ... Chediak-Higashi syndrome ... diagnosis #causes #hematology
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD)

Pathophysiology:
Pyrophosphate produced by chondrocytes likely precipitates with calcium to
weird joints (shoulders ... Acute Pseudogout: Treatment ... Crowned Dens Syndrome ... present with acute neck ... Deposition #Disease #Rheumatology
Anti-NXP-2 Dermatomyositis

What?
DM with generalized subcutaneous edema
Pts have more myalgias, more severe weakness, and an increased prevalence
weakness in the neck ... , and back and shoulders ... positive patients Treatment ... Prednisone at 1 mg/kg ... diagnosis #management #rheumatology