22 results
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
Glomerular Diseases ... RBC casts in urine ... diabetes)) #Glomerular ... #Diseases #Nephritic ... #Nephrology #Diagnosis
Causes of Proteinuria - Differential Diagnosis Algorithm
Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Causes of Proteinuria ... • Fanconi's syndrome ... • Drugs Glomerular ... Minimal change disease ... #Nephrology #Differential
Hematuria Workup and Diagnosis Algorithm
 • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
Hematuria Workup ... • Evidence of glomerular ... bleeding (proteinuria ... if cause not identified ... Diagnosis #Algorithm #Workup
Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
hematuria and/or proteinuria ... the patient have glomerular ... hematuria (RBC casts ... dysmorphic RBCs in urine ... Comparison #Algorithm #Nephrology
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
basement membrane disease ... - Alport syndrome ... - Proteinuria ... disease Renal ... #urology #nephrology
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
hemolytic-uremic syndrome ... arbitrarily defined as urine ... because nephritic urine ... Nephrocalcinosis causes ... #syndrome #nephrology
Recommended initial testing for patients being evaluated for glomerular disease 

24-hour urine collection - Quantify proteinuria.
disease 24- ... hour urine collection ... infections are common causes ... of glomerular disease ... #testing #workup
Recommended initial testing for patients being evaluated for glomerular disease
1) 24-hour urine collection - Quantify proteinuria.
hour urine collection ... infections are common causes ... of glomerular disease ... #glomerular #disease ... #workup #diagnosis
Urinalysis & Urine Sodium 
Theophilus Protospatharius, a seventh-century physician who wrote the first manuscript focused exclusively
Sodium Theophilus ... proteins, documenting proteinuria ... as a disease state ... • Urinary casts ... #UNa #casts #glucosuria
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN
 • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
GN • Active Urine ... , +/- proteinuria ... formation along glomerular ... (Dense deposit disease ... anti-phospholipid syndrome