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rheumatology differential erythematosus systemic joint signs pain syndrome antinuclear approach classification disease disorders druginduced monoarthritis monoarticular neurology patterns polyarthritis polyarticular
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
erythematosus (SLE ... Juvenile Idiopathic Arthritis ... #Antinuclear #Antibodies ... #ANA #patterns ... #rheumatology #diagnosis
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... Antibody refers to antibodies ... context of other symptoms ... #Antinuclear #Antibodies ... #rheumatology #diagnosis
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms ... , Arthritis, myalgia ... • Immunologic Workup ... constitutional symptoms ... #diagnosis #management
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
: - Arthritis ... Auto-Antibodies ... : - ANA 95-100% ... and Lupus Mimickers ... autoantibodies #signs #symptoms
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
(SLE): Musculoskeletal ... - Arthralgia, Arthritis ... #MSK #Musculoskeletal ... pathophysiology #signs #symptoms ... #diagnosis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Differential Diagnosis ... Malignancy (e.g. hematologic ... pain • Swan neck/Ulnar ... : • Symptoms limited
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... and Management ... • Immunologic Workup ... Erythematosus #Diagnosis ... #rheumatology
Joint Disorders - Differential Diagnosis Algorithm Monoarthritis • Septic • Crystalline - Gout
- Differential Diagnosis ... of Lumbar Spine and ... Erythematosus (SLE ... should have other symptoms ... Joint #Disorders #msk
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
• Arthritis domain ... pericarditis • Hematologic ... Highly specific antibodies ... Classification #Criteria #SLE ... Erythematosus #diagnosis
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential Diagnosis ... and Workup History ... pylori test (GI symptoms ... (e.g., SLE), anti-phospholipid ... antibodies, Quantitative
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