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diagnosis hematology causes classification lactate typea typeb algorithm aniongap atlas elevation erythematosus extravascular ferritin hemolysis hemolytic intravascular kilu lupus mcv
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
• Microcytic - Iron-deficiency ... , Thalassemia, Iron-deficiency ... Morphology #Atlas #key ... #diagnosis #differential ... #hematology
Iron Deficiency Anemia - Differential Diagnosis Algorithm Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR • Blood loss:
Iron Deficiency ... Anemia - Differential ... Gastrectomy, WHDA syndrome ... #Deficiency #Anemia ... #Differential #
Lactic Acidosis - Classification and Differential Diagnosis Type A Lactic Acidosis: Inadequate Oxygen Delivery • Anaerobic muscular
Lactic Acidosis ... delivery: Hypoxemia, Anemia ... Type B Lactic Acidosis ... failure, Short bowel syndrome ... , Thiamine deficiency
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
Microcytic" • Iron ... deficiency • ... Myelodysplastic syndrome ... morphologic #mcv #differential ... diagnosis #causes #hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Thrombocytosis - Differential ... malignancies • Anemia ... (specifically: iron ... deficiency, hemolysis ... Myelodysplastic syndrome
Metabolic Acidosis with Anion Gap - KILU Mnemonic K - Ketoacidosis • DKA - With normal glucose, ask if
Metabolic Acidosis ... normal glucose, ask ... inhibitors and SGLT2 deficiency ... (rare in lit), iron ... #diagnosis #differential
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
) - HELLP syndrome ... - Drugs (Beta lactam ... G6PD deficiency) ... Extravascular #Causes #differential ... #anemia
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
Acidosis - Differential ... - Compartment syndrome ... 30mmHg) - Severe anemia ... effect - Thiamine deficiency ... #Differential #
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
or folic acid deficiency ... treatments • Copper deficiency ... rings of excess iron ... blood count with differential ... #diagnosis #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... Non-autoimmune rheumatologic ... disease • Prolidase deficiency ... pain • Swan neck/Ulnar ... lymphopenia, low PLT • Anemia
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