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diagnosis hematology causes algorithm workup classification hemolytic pancytopenia rbc atlas dermatology hemolysis macrocytic morphology nutrition platelets secondary systemic agglutinin approach
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
- Differential ... malignancies • Anemia ... specifically: iron deficiency ... Chronic inflammatory disorders ... Myelodysplastic syndrome
Thrombocytosis - Differential Diagnosis Platelet Count > 450 Reactive: • Anemia/blood loss (Fe deficiency) • Infection/Sepsis • Non-infectious
Thrombocytosis - ... Differential Diagnosis ... Reactive: • Anemia ... blood loss (Fe deficiency ... Non-infectious (malignancy, rheumatologic
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
- Differential ... • Rheumatic disorders ... malignancy • Iron deficiency ... anemia #Thrombocytosis ... #Differential #
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
- Markers and Differential ... Pelger-Huet, Macrocytic anemia ... Amy Chung, MD, MSc ... #hematology #Markers ... #Differential #
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... Acute hemolysis, deficiency ... anemia, Rebound ... Kawasaki, Nephrotic syndrome ... #Platelets #Differential
Anemia - Underproduction Diagnostic Algorithm - Iron deficiency anemia - Anemia of chronic inflammation - Anemia
Algorithm - Iron deficiency ... and/or folate deficiency ... Probable bone marrow disorder ... Underproduction #Algorithm #hematology ... #diagnosis #differential
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
- Differential ... • B12/Folate Deficiency ... • RBC Membrane Disorder ... RBC Metabolism Disorder ... Algorithm #Causes #Hematology
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Microcytic - Iron-deficiency ... Myelodysplastic syndrome ... Hemolytic uremic syndrome ... key #diagnosis #differential ... #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Volume (MCV) - Differential ... • Dietary Deficiency ... • Small Bowel Disorder ... Myelodysplastic Syndromes ... B12 and Folate Deficiency
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
RBC: Pyridoxine deficiency ... Thalassemia, Iron deficiency ... Unstable hemoglobin disorders ... RBC #Morphology #differential ... #diagnosis #hematology
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