41 results
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Platelet Count - Differential ... Rebound effect from treatment ... Inflammatory Conditions: Rheumatologic ... Vasculitides, IBD, Celiac disease ... Kawasaki, Nephrotic syndrome
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Initial screening test ... block • Sjogren syndrome ... Treatment: • ... Summary #diagnosis #rheumatology ... #management
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's Disease ... fraction < 20% Differential ... Diaqnoses: • Infectious ... #diagnosis #management ... #treatment #rheumatology
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Drug-associated, PCH, Evans Syndrome ... Internal (RBC) - Infections ... Laboratory Tests ... #Diagnosis #hematology
Hearing Loss - Differential Diagnosis Framework

Hearing Loss Types:
• Conductive
• Sensorineural
• Mixed
Presbycusis is the most common type
Hearing Loss - Differential ... Infection or cancer ... Onset ○ Meniere disease ... II ○ Susac’s syndrome ... ○ HIV ○ Lyme disease
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
life-threatening Differential ... /Edrophonium test ... - Repetitive nerve ... precipitated by: Drugs, infection ... Gravis #diagnosis #management
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
is a skin prick test ... ) Differential Diagnosis ... Arthritis, AS Treatment ... #diagnosis #management ... signs #symptoms #rheumatology
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
von Willebrand Syndrome ... Diagnosis and Management ... thrombocythemia), Autoimmune disease ... #treatment #hematology ... #differential
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... younger pts) Differential ... • Diagnostic Test ... Donath-Landsteiner test ... hemolytic #anemia #hematology
Approach to Joint Pain

History:
Is the pain from:
	• Joint
	• Adjacent bursa
	• Tendon
	• Ligament
	• Bone
	• Muscle
	• Referred from
visceral organ or nerve ... Calcium oxalate Infectious ... Acute or chronic infections ... Joint #Pain #MSK #rheumatology ... approach #workup #differential