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Initial Clinical and Laboratory Data Base for Defining Major Syndromes in Nephrology

#Major #Syndromes #Nephrology #Diagnosis #Workup
Initial Clinical ... Defining Major Syndromes ... #Major #Syndromes ... #Nephrology #Diagnosis ... #Differential #Table
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
Anticentromere - CREST syndrome ... La) - Sjogren's syndrome ... Goodpasture's syndrome ... Associations #diseases #diagnosis ... #table #rheumatology
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
block • Sjogren syndrome ... polymyositis overlap syndrome ... #Summary #diagnosis ... #rheumatology # ... management
Inherited Arrhythmia Syndromes
Entity - Prevalence / Incidence - Diagnosis - Arrhythmic Presentation - Management
 • Long
• Long QT Syndrome ... Normal Heart • Short ... #clinical #cardiology ... #diagnosis #management ... #table
Myositis Specific Antibodies (MSAs)

Dermatomyositis: MDA5, TIF1y, NXP2, Mi-2, SAE
Anti-Synthetase Syndrome: Jo-1, PL7, PL12, EJ, OJ
Immune Mediated
TIF1y, NXP2, Mi-2, SAE ... Anti-Synthetase Syndrome ... Antibodies #MSAs #clinical ... #diagnosis #rheumatology ... #table
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
Hypereosinophilic Syndrome ... Hypereosinophilic Syndrome ... • Clinically ... Hypereosinophilic #Syndrome ... #management #algorithm
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
• Lupus (SLE): ... Antiphospholipid Antibody Syndrome ... LAC) • Sjogren Syndrome ... #diagnosis #associations ... #table
Monteggia Fracture 
Fracture of proximal ulnar shaft with radial head dislocation. Remember “MUGR” to recall where
Fracture of proximal ulnar ... Peak age 4-10 • Ulna ... ), compartment syndrome ... • If stable ... Radiology #XRay #Diagnosis
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
GI - Felty syndrome ... • Felty's syndrome ... - SLE Neurologic ... , Behçet's syndrome ... #rheumatology
Connective tissue disease-associated interstitial lung diseases

LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
PSS: Sjogren syndrome ... rheumatoid arthritis SLE ... LungDisease #CTILD #Diagnosis ... Differential #Comparison #Table ... #Pulmonary #Rheumatology