10 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... Disease, PRES Pathophysiology ... Erythematosus #SLE ... #CNS #neurology ... #rheumatology #
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
constitutional symptoms • Treatment ... Discontinuation of causal ... life-threatening • Treatment ... #table #rheumatology ... #diagnosis #management
Top 10 situations when to think about lupus
1) Inflammatory joint pain (especially in the wrists and
especially in the wrists ... the face (many differential ... diagnoses, including ... children (pediatric SLE ... #diagnosis #sle
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... permanent alopecia Differential ... Diagnosis: • ANCA-associated ... Malignancy (e.g. hematologic ... pain • Swan neck/Ulnar
Spinal Cord Injury by Nerve Root Levels
Spinal Root	Sensory	Motor	Reflex
C4	Acromioclavicular Joint	Respiration	None
C5	Radial Antecubital Fossa	Elbow Flexion	Biceps Reflex
C6	Dorsal Thumb	Wrist Extension	Brachioradialis Reflex
C7	Dorsal
C6 Dorsal Thumb Wrist ... Flexion None T1 Ulnar ... Abduction None T7-T12 See ... NerveRoots #Levels #differential ... #diagnosis #Neurology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
skin injury) • Neurologic ... Behcet disease) Differential ... Oral aphthae : SLE ... • Arthritis: SLE ... Arthritis, AS Treatment
Drug Induced Systemic Lupus Erythematosus
> 100 drugs have been associated with drug-induced SLE
High risk (>5%):
 •
Induced Systemic Lupus ... with drug-induced SLE ... for 1 year of treatment ... pharmacology #risk #differential ... #diagnosis #rheumatology
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... Disorders: - SLE ... Transverse Myelitis Treatment ... #management #neurology ... #differential
Drug Induced Lupus (DIL)
 • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
is rare in DIL, SCLE-DIL ... constitutional symptoms • Treatment ... Discontinuation of causal ... #DIL #rheumatology ... #diagnosis #treatment
TAFRO

TAFRO syndrome was first described in 2010, standing for:
- Thrombocytopenia
- Anasarca
- Fever
- Reticulin fibrosis
- Organomegaly

TAFRO syndrome
including systemic lupus ... erythematosus (SLE ... cell lymphoma Pathophysiology ... Histopathological Diagnoses ... Hypoalbuminemia Treatment