38 results
Tramadol - Toxicology
Due to different CYP-2D6 genotypes, people variably metabolize tramadol into its active metabolite, M1
This
people variably metabolize ... into its active metabolite ... codeine ultra-rapid metabolism ... activity as the M1 metabolite ... in poor codeine metabolism
Plain radiography of the abdomen revealed calcification of both adrenal glands. A homozygous mutation in LIPA
autosomal recessive metabolic ... critical for the metabolism ... and gut, which causes ... NEJM #Wolmans #radiology
Toxic Alcohol Metabolism and Metabolites

#Toxic #Alcohol #Metabolism #Metabolites #Toxicology #Pharmacology
Toxic Alcohol Metabolism ... Toxic #Alcohol #Metabolism ... #Metabolites #Toxicology ... #Pharmacology
Tranexamic Acid - Indications and Pharmacology
Pharmacokinetics:
 • MOA: Inhibits plasminogen activation to plasmin & inhibits fibrinolysis
Indications and Pharmacology ... angioedema) • Metabolism ... amount of hepatic metabolism ... : Urine Common Uses ... #Indications #Pharmacology
Etiologies of dilated cardiomyopathy. HF, heart failure; HFrEF, heart failure with reduced ejection fraction; HIV, human
- Endocrine / metabolic ... differential #diagnosis #cardiology ... #causes
Salicylate Toxicity - Diagnosis and Management

Consider if:
1) Patient is hot and altered
2) You see tachypnea with
no respiratory cause ... show anion-gap metabolic ... exposure Symptoms: Nausea ... Labs: Anion-Gap Metabolic ... Aspirin #Toxicity #Toxicology
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
Reticulocytes, Increased Unconjugated ... Disorder • RBC Metabolism ... Diagnosis #Algorithm #Causes
Considerations for Crystalloids - 0.9% NS vs LR vs Plasma-Lyte
 - Causes hyperkalemia?
 - Safe to
Plasma-Lyte - Causes ... - Causes lactic ... - Can cause a NAGMA ... patients with a metabolic ... #Crystalloids #pharmacology
Clozapine Toxicology
Clozapine is an atypical antipsychotic most often reserved for use in patients who have treatment-resistant
Clozapine Toxicology ... following first-pass metabolism ... - Metabolism - ... Clozapine is known to cause ... Toxicity #Diagnosis #Pharmacology
Serotonin Syndrome Drug Precipitants and Pharmacology
↑ Serotonin Formation: Tryptophan, Oxitriptan
↑ Serotonin Release: Amphetamines, Cocaine, Mirtazapine
↑ Serotonin
Precipitants and Pharmacology ... Lithium ↓ Serotonin Metabolism ... Serotonin #Syndrome #Pharmacology ... #medications #causes