39 results
Laboratory Testing in Hemolytic Anemia

Intravascular vs Extravascular Hemolysis
Reticulocytes
Unconjugated bilirubin
LDH
Peripheral smear
Haptoglobin
Urine hemosiderin
Urine hemoglobin
Carboxyhemoglobin

#Hemolytic #Anemia #Laboratory #Testing #workup
Laboratory Testing ... Reticulocytes Unconjugated ... Anemia #Laboratory #Testing ... workup #diagnosis #hematology
Jaundice - Differential Diagnosis Algorithm
Pre-Hepatic - Unconjugated Hyperbilirubinemia
Increased Production
 • Hemolysis
 • Ineffective Erythropoiesis
 • Hematoma
Decreased
Pre-Hepatic - Unconjugated ... • Gilbert's Syndrome ... Crigler-Najjar Syndromes ... II) Hepatic - Conjugated ... Algorithm #Causes #Hepatology
Inherited Non-hemolytic Disorders of Hyperbilirubinemia 

== Disorders of Conjugation ==
Gilbert Syndrome:
 • 5-10% of the population
hyperbilirubinemia syndrome ... , intermittent unconjugated ... UGT1A1 activity • Unconjugated ... and unconjugated ... Congenital #bilirubin #hepatology
Commonly Observed Laboratory Findings in Hepatic / Liver Failure
 - Elevated conjugated and unconjugated bilirubin -
Failure - Elevated conjugated ... and unconjugated ... the hepatorenal syndrome ... LiverFailure #Hepatic #Hepatology ... Laboratory #Diagnosis #Testing
Yao Syndrome vs VEXAS

Zhuoer Xie, MD @ZhuoerXie

#Yao #Syndrome #VEXAS #diagnosis #comparison #rheumatology
Yao Syndrome vs ... ZhuoerXie #Yao #Syndrome ... VEXAS #diagnosis #comparison ... #rheumatology
Stevens-Johnson syndrome (SJS), Toxic epidermal necrolysis (TEN) and Overlap

 SJS-TEN overlap and TEN - Surface Epidermal
Stevens-Johnson syndrome ... Stevens #Johnsons #Syndrome ... Epidermal #Necrolysis #Comparison ... #Diagnosis #Dermatology
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Drug-associated, PCH, Evans Syndrome ... Reticulocyte Count ↑ - Unconjugated ... Differential #Diagnosis #hematology
Thrombotic Microangiopathy - TTP VS HUS

Big picture points : Often hard to differentiate the two entities,
awaiting confirmatory testing ... thrombocytopenia #Comparison ... Diagnosis #Table #Hematology
Multi-System Inflammatory Syndrome in Children (MIS-C) vs. Kawasaki Disease
CDC Case Definition for MIS-C;
 • < 21
Multi-System Inflammatory Syndrome ... Positive COVID testin ... MISC #Kawasaki #Comparison ... #Inflammatory #Syndrome
Idiopathic Inflammatory Myopathies - 
Dermatomyositis (DM), Immune-Mediated Necrotizing Myopathy (IMNM), Antisynthetase Syndrome (ASS), Inclusion Body Myositis
Antisynthetase Syndrome ... Idiopathic #Myopathy #Comparison ... Managment #algorithm #Rheumatology