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Suggested algorithm for follow-up of monoclonal gammopathy of undetermined significance (MGUS)
Mayo Clinic Risk Stratification Model. CBC,
gammopathy of undetermined ... significance (MGUS ... monoclonal #gammopathy #MGUS
Suggested algorithm for bone marrow biopsy and skeletal imaging in patients with monoclonal gammopathy of undetermined
gammopathy of undetermined ... significance (MGUS ... 1.5 gm/dL) IgM MGUS ... , low-risk MGUS ... 8) light-chain MGUS
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework

Hematologic disorder characterized by the presence of either
Gammopathy of Undetermined ... Significance (MGUS ... Prevalence M > F MGUS ... IgM MGUS: • Serum ... Monoclonal #Gammopathy #Undetermined
Amyloidosis Diagnosis
1) Patient presentation
 • Cardiac-specific signs of amyloidosis: Diastolic heart failure, Heart failure with preserved
gammopathy of undetermined ... significance (MGUS ... neuropathy, atypical MGUS
Complications of Monoclonal Gammopathy of Undetermined Significance (MGUS)
Fracture, Osteoporosis
 - Increased osteoclast activity and bone resorption
Gammopathy of Undetermined ... Significance (MGUS ... high-risk situations #MGUS
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
gammopathy of undetermined ... significance (MGUS
Monoclonal Gammopathy Testing
Strengths, Weaknesses and Accuracy Compared
 - SPEP 
 - IFE 
 - FLC
Protein #Diagnosis #MGRS ... #MGUS #SPEP #IFE
Monoclonal Gammopathy of Clinical Significance (MGUS) - Differential Diagnosis

Neurologic-Centered:
 (+) Systemic Features: POEMS, AL amyloid, Cryoglobulinemia
Significance (MGUS ... Renal-centered (ie "MGRS ... #Significance #MGUS
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
• MM • WM • MGUS ... • MGCSMGRS ... Dermato-neuro syndrome) MGRS
MGRS - Monoclonal Gammopathy of Renal Significance 

#MGRS #Monoclonal #Gammopathy #Renal #Significance #Diagnosis #Pathology
MGRS - Monoclonal ... Significance #MGRS