17 results
Oxygen-Hemoglobin Dissociation Curve

Left Shift (↓ O2 unloading to tissue), Left = Lower:
 • ↓ H+ (↑
Left Shift (↓ O2 unloading ... Right Shift (↑O2 unloading ... Dissociation #Curve #pathophysiology
Stress Fracture: Pathogenesis and clinical findings
Abnormal biomechanics, Repetitive impact activities
=> Repetitive subthreshold mechanical loading
=> Bone strain
=>
subthreshold mechanical loading ... from continued loading ... #orthopedics #pathophysiology
Oxyhemoglobin Dissociation Curve 

Left Shift - decreased unloading of O2 at tissue level (i.e.  increased
Shift - decreased unloading ... Shift - increased unloading ... Dissociation #Curve #Pathophysiology ... #Right #Shift #Differential
Non-cirrhotic Hyperammonemia - Differential Diagnosis Framework

Hematologic & Vascular:
 • Multiple myeloma & Acute leukemia (plasma cells
Hyperammonemia - Differential ... bleeding (↑ nitrogen loading ... Hyperammonemia #ammonia #Differential ... #Diagnosis #Pathophysiology
Differentiation of Causes of Hyperthyroidism According to Pattern of Radionucleotide Uptake
Reduced uptake:
 • Thyroiditis
 • Exogenous
thyroxine • Iodine loading ... radionuclide #uptake #differential
Polyuria - Differential Diagnosis Algorithm
Urine Output > 3L /day
Water Diuresis (Urine Osm <100 mOsm/kg)
 • Primary
Polyuria - Differential ... Water and solute loading ... #Polyuria #Differential
Disc Herniations - Pathogenesis and Complications
• 90% of Lumbar disc herniations happen at L4/5 and L5/S1
•
-> Mechanical loading ... complications #msk #pathophysiology
Osteoarthritis (OA): Clinical findings
 • Stimulation of joint nociceptors in subchondral bone -> Pain with loading
bone -> Pain with loading ... Osteoarthritis #OA #pathophysiology
Hypochloremia - Differential Diagnosis Algorithm

Cause - Decreased Intake:
 • Low salt in diet
 • Exclusive D5W
Hypochloremia - Differential ... facilitates oxygen unloading ... Hypochloremia #Differential ... Diagnosis #Algorithm #Pathophysiology
Drug-Induced Edema
Drug-induced edema is caused by many drugs & can coincide with or worsen pre-existing peripheral
blood vessels, leading ... Medication #Causes #Differential ... #Pharmacology #Pathophysiology