154 results
Stress Fracture: Pathogenesis and clinical findings
Abnormal biomechanics, Repetitive impact activities
=> Repetitive subthreshold mechanical loading
=> Bone strain
=>
subthreshold mechanical loading ... from continued loading ... StressFractures #msk ... #orthopedics #pathophysiology
Oxygen-Hemoglobin Dissociation Curve

Left Shift (↓ O2 unloading to tissue), Left = Lower:
 • ↓ H+ (↑
Left Shift (↓ O2 unloading ... Right Shift (↑O2 unloading ... Dissociation #Curve #pathophysiology
Oxyhemoglobin Dissociation Curve 

Left Shift - decreased unloading of O2 at tissue level (i.e.  increased
Shift - decreased unloading ... Shift - increased unloading ... Dissociation #Curve #Pathophysiology
VA ECMO Unloading - LV Venting
Different LV Venting Strategies work through these basic mechanisms: ↓ Preload,
VA ECMO Unloading ... karanpdesai #VAECMO #Unloading
Disc Herniations - Pathogenesis and Complications
• 90% of Lumbar disc herniations happen at L4/5 and L5/S1
•
-> Mechanical loading ... complications #msk ... #pathophysiology
Low Ankle Sprain: Pathomechanics and Clinical Findings

Grading Ligament Sprains
l: Minimal ligament disruption, mild swelling & tenderness,
Clinical Findings Grading ... ligament substance leading ... LowAnkleSprain #Sports #MSK ... #orthopedics #Grading ... Grades #Diagnosis #pathophysiology
Oral anticoagulant dosing and bridging for VTE

- Dr. Joseph Shatzel @Clotmaster 

#VTE #DOAC #Bridging #Dosing #Oral
Rivaroxaban #Edoxaban #Loading
Algorithm for Evaluation and Treatment of Asymptomatic Candiduria
Evidence for disseminated candidiasis, Unstable or neutropenic patient
1. fluconazole
caspofungin 70 mg iv loading ... anidulafungin 200mg iv loading
Non-cirrhotic Hyperammonemia - Differential Diagnosis Framework

Hematologic & Vascular:
 • Multiple myeloma & Acute leukemia (plasma cells
bleeding (↑ nitrogen loading ... Differential #Diagnosis #Pathophysiology
Systemic Lupus Erythematosus: Gastrointestinal Manifestations
 - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Syndrome - Protein-Losing ... Abdominal pain, bloating ... Complications #pathophysiology