20 results
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... Gitelman Syndrome ... thiazide-sensitive sodium-chloride ... #Syndrome #Pathophysiology ... #nephrology #diagnosis
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Differential Diagnosis Algorithm ... , Gitelman syndrom ... Differential #Diagnosis #Algorithm ... #causes #potassium ... #low #nephrology
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
Inherited Defects ... ascending limb Gitelman ... Increased open time and ... of epithelial sodium ... #Kidney #Nephrology
Hypomagnesemia - Etiologies by Mechanism

Decreased GI Uptake 
 - Poor dietary intake (particularly common in alcoholics)
Medications - Loop and ... - Gitelman ... Genetic defects ... Classification #Causes ... #Workup #hypomg
Causes of Hypokalemia - Differential Diagnosis Algorithm
Defining the cause of hypokalemia starts by measuring urinary K
Differential Diagnosis Algorithm ... • Skin and/or ... , Gitelman's syndrome ... differential #diagnosis #algorithm ... #causes #nephrology
Causes of Hypomagnesemia - Differential Diagnosis Algorithm
GI LOSS - FeMg < 2-2.5% or 24h Urine Mg
Causes of Hypomagnesemia ... Differential Diagnosis Algorithm ... nephrocalcinosis (FHHNC) • Gitelman's ... syndrome • Thiazide ... ab • Genetics defects
Hypernatremia Diagnosis and Workup

Step 1 . Repeat the sodium concentration.
Step 2.  Check plasma osmolality.
NORMAL PLASMA
Hypernatremia Diagnosis and ... Workup Step ... Repeat the sodium ... • nephrotic syndrome ... #Algorithm #Nephrology
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Kidney Injury - AKI Workup ... Algorithm and Differential ... electrolytes, urea ... #Diagnosis #nephrology ... #causes
Management of SIADH
Treat underlying cause:
 • Causes can include pain, primary lung pathology, post-operative phenomenon, medications,
volume overload Urea ... promoting passive sodium ... into ammonium by urease-producing ... Has many side effects ... #hyponatremia #nephrology
Hyponatremia - Differential Diagnosis Algorithm
Hypovolemic - Give volume
Hypervolemic (Edematous) - Look for and treat underlying cause
Differential Diagnosis Algorithm ... treat underlying cause ... cirrhosis, nephrotic syndrome ... #diagnosis #nephrology ... #sodium