12 results
Hyponatremia Differential Diagnosis Algorithm - Utilizing Uric Acid 
ADH promotes Urea/uric acid excretion along with water
ADH promotes Urea ... Uric Acid - Low ... High Uric Acid → renal ... #nephrology #sodium ... #low #uricacid
Mechanisms of nephron damage in cardiorenal syndrome
 • Increased renal interstitial pressure
 • Hypoperfusion
 • Reduced
• Increased renal ... blood flow • ... hypertrophy • Sodium ... #Mechanisms #pathophysiology ... #nephrology
Volume Based Approach to Hyponatremia
Hypovolemic, Serum uric acid >4
 • Urine Na <20: Extra-renal losses
 •
Hypothyroidism, Low ... Cirrhosis, Nephrotic syndrome ... #Hyponatremia #algorithm ... #diagnosis #sodium ... #low #nephrology
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
Diagnosis Workup Algorithm ... mOsm/kg - Implies renal ... • Euvolemic (Low ... , Cushing syndrome ... #nephrology #sodium
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
normal volume-based algorithm ... Sodium loss (diuretics ... can be high or low ... Cirrhosis, Nephrotic syndrome ... #nephrology
Hepatorenal Syndrome (HRS)

Definition:
• Functional, potentially reversible kidney impairment.
• Occurs in advanced liver disease: cirrhosis, severe alcoholic
Pathophysiology: ... Classification: ... • Associated with ... • Urine sodium ... #Hepatology #Nephrology
Hyponatremia - Differential Algorithm
Isotonic Hyponatremia: Hyperlipidemia, Hyperproteinemia, Recent TURP
Hypotonic Hyponatremia: 
 • Hypovolemia: Diuretics/Nephropathies, Vomiting, Diarrhea,
- Differential Algorithm ... Cirrhosis, Nephrotic Syndrome ... , Chronic Renal ... diagnosis #causes #nephrology ... #sodium #low
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
pulmonary and renal ... • Cogan Syndrome ... • Complement (Low ... • Urinalysis (Renal ... #rheumatology #classification
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
HIV dementia Pathophysiology ... ARVs can have low ... volume • Patchy areas ... The clinical syndrome ... untreated HIV and with low
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
thiazide-sensitive sodium ... alkalosis • Normal or low ... , Renal tubular ... #diagnosis #nephrology ... #management #pathophysiology