6 results
Pathophysiology of Tumor Lysis Syndrome (TLS)
Tumor Cell Lysis
-> Release of DNA
 • Purines -> Hypoxanthine /
Pathophysiology ... of Tumor Lysis Syndrome ... excretion) • Phosphorus ... Precipitation => • Urate ... #TumorLysis #Syndrome
Hypophosphatemia Diagnostic Algorithm
- GI Losses
- Redistribution
- 1° HPT
- 1° Renal PO4 wasting: Hereditary, TIO, Fanconi Syndrome,
, TIO, Fanconi Syndrome ... Hypophosphatemia #phosphorus ... #low #diagnosis ... #Algorithm #differential ... #nephrology
Hypophosphatemia - Differential Diagnosis Algorithm
Appropriately Low Kidney Phosphate Excretion:
 • Decreased GI Absorption: Chronic Diarrhea, Antacids,
Appropriately Low ... Shift: Refeeding Syndrome ... Tumor Genesis Syndrome ... FGF23: Fanconi Syndrome ... #nephrology #phosphorus
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
normal volume-based algorithm ... can be high or low ... Cirrhosis, Nephrotic syndrome ... differential #diagnosis #table ... #sodium #nephrology
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
HIV dementia Pathophysiology ... ARVs can have low ... volume • Patchy areas ... The clinical syndrome ... untreated HIV and with low
Causes of Hyperkalemia - Intercellular Shift - Differential Diagnosis Algorithm
Transcellular Shift - Appropriate renal excretion (GFR,
Differential Diagnosis Algorithm ... , TTKG, distal flow ... Osmoles, Increased Urate ... Tumor Lysis Syndrome ... IntercellularShift #Nephrology