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diagnosis differential treatment calcium causes gitelman hypercalcemia hypocalcemia hypokalemia hyponatremia hypotonic intercellularshift k neurology parathyroid person physiologic potassium sodium sps
Workup of Hypercalcemia - Differential Diagnosis Algorithm High or Normal PTH: • Hyperparathyroidism: Parathyroid adenoma, Parathyroid hyperplasia,
Workup of Hypercalcemia ... Differential Diagnosis Algorithm ... Low PTH: • High ... PTHrP: - Low ... #Workup #nephrology
Pathophysiology of Tumor Lysis Syndrome (TLS) Tumor Cell Lysis -> Release of DNA • Purines -> Hypoxanthine /
Pathophysiology ... of Tumor Lysis Syndrome ... -> Uric Acid (low ... Precipitation => • Urate ... Hypocalcemia • Hyperkalemia
Hypocalcemia Workup - Differential Diagnosis Algorithm • Low Magnesium, High Magnesium - Functional Hypoparathyroidism • High
Hypocalcemia Workup ... PTH - Hypoparathyroidism ... Phosphate, High PTH ... metastases, Hungry bone syndrome ... #nephrology #calcium
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
S/Sx: Most pts ... reabsorption) Workup ... Elimination (see Table ... acidosis) • Low ... Treatment #potassium #nephrology
Physiologic Approach to Hypotonic Hyponatremia The next time you have a case of hypotonic hyponatremia, give the
normal volume-based algorithm ... : Hypovolemia, Hypervolemia ... Cirrhosis, Nephrotic syndrome ... differential #diagnosis #table ... #sodium #nephrology
Causes of Hyperkalemia - Intercellular Shift - Differential Diagnosis Algorithm Transcellular Shift - Appropriate renal excretion (GFR,
Causes of Hyperkalemia ... , TTKG, distal flow ... Osmoles, Increased Urate ... Tumor Lysis Syndrome ... IntercellularShift #Nephrology
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary Epidemiology: • Prevalence: 1-2 cases per million -
Diagnosis and Management ... Pathophysiology ... positive in 2/3 of pts ... antibody that works ... SPS #Diagnosis #Management
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
• Unexplained hypokalemia ... alkalosis • Normal or low ... #diagnosis #nephrology ... #management #pathophysiology ... #Hypokalemia
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