10 results
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
Inherited Defects ... ascending limb Gitelman ... Increased open time and ... #Kidney #Nephrology ... #Differential #Table
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
HIV dementia Pathophysiology ... infects the CNS ... volume • Patchy areas ... The clinical syndrome ... ataxia
Alexia Without Agraphia
Alexia without agraphia is a disconnection syndrome where patients cannot read but can write.
disconnection syndrome ... comprehension and ... Pathophysiology: ... Agraphia #clinical #neurology ... #diagnosis #pathophysiology
Causes of Hypokalemia
Transcellular Shifts:
 - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
hypomagnesemia), Eating disorders ... diuretic use), Gitelman's ... syndrome (mimics ... megaloblastic anemia ... differential #diagnosis #nephrology
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
pernicious anemia ... Pathophysiology ... other neurological disorders ... limb or joint disorders ... Management #treatment #neurology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Immunodeficiency disorder ... • Affects 1:25,000 ... breast cancer ... : • Nephrotic syndrome ... (Epstein-Barr syndrome
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
Spinal Cord Disorders ... often- Sensory ataxia ... MCTD, Sjogren syndrome ... #diagnosis #neurology ... differential #algorithm
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
• Or brainstem syndromes ... Afferent pupillary defect ... impairment, Mood disorder ... Cramping, Weakness, Ataxia ... diagnosis #management #neurology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
Suspect in movement disorders ... Symptoms: AMS, motor deficits ... , gait ataxia, and ... periventricular areas ... InfectiousDiseases #Neurology
Rhabdomyolysis - Differential Diagnosis Framework
Rhabdomyolysis = Destruction of skeletal muscle with leakage of contents into circulation.
Compression • Genetic Defects ... Mitochondrial disorders ... Neuroleptic malignant syndrome ... Diagnosis #Causes #nephrology ... #table