10 results
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... Gitelman Syndrome ... thiazide-sensitive sodium-chloride ... #Syndrome #Pathophysiology ... #nephrology #diagnosis
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
Gitelman Syndrome ... thiazide-sensitive sodium ... Rhabdomyolysis Treatment ... #nephrology #management ... #pathophysiology
Hyponatremia - Differential Diagnosis Algorithm
Hypovolemic - Give volume
Hypervolemic (Edematous) - Look for and treat underlying cause
Differential Diagnosis Algorithm ... cirrhosis, nephrotic syndrome ... always exclude: CKD ... #diagnosis #nephrology ... #sodium
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
Urinary Chloride Algorithm ... diuretic use, Bartter syndrome ... , Gitelman syndrome ... the excretion of sodium ... #nephrology #differential
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Injury - AKI Workup Algorithm ... electrolytes, urea ... • Cardio-renal syndrome ... #AKI #Workup #Algorithm ... Differential #Diagnosis #nephrology
Pruritus Treatment Algorithm for Hemodialysis Patients 

Non-PharmacoIogicaI Measures 
 • Use gentle soap e.g. Dove
Pruritus Treatment ... Algorithm for Hemodialysis ... except if other areas ... Uremia #Management #Nephrology ... #CKD
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
Pathophysiology ... Treatment: • ... others (botox, sodium ... Diagnosis #Management #treatment ... #neurology
Hepatorenal Syndrome (HRS)

Definition:
• Functional, potentially reversible kidney impairment.
• Occurs in advanced liver disease: cirrhosis, severe alcoholic
Hepatorenal Syndrome ... Pathophysiology: ... • Urine sodium ... Treatment Overview ... #Hepatology #Nephrology
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
HIV dementia Pathophysiology ... volume • Patchy areas ... The clinical syndrome ... Treatment: • HAART ... treatment • Cognitive
Management of Pruritus in Patients with Chronic Kidney Disease
Pruritus with no primary lesions - differential diagnosis:
wool, over itchy areas ... #Pruritus #Treatment ... #Algorithm #Hemodialysis ... Uremia #Management #Nephrology ... #CKD