15 results
Atlas of Urine Microscopy Findings
 • Epithelial cells - Normal
 • Renal tubular cells - Acute
Atlas of Urine Microscopy ... red - cells Non-glomerular ... also be seen if urine ... renal disease • Granular ... key #diagnosis #nephrology
Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
the patient have glomerular ... hematuria (RBC casts ... urine)? ... #Comparison #Algorithm ... #Nephrology #Diagnosis
Urine Microscopy - Casts
Acellular Casts
 • Hyaline Casts - Consists of only precipitated Tamm-Horsfell protein without
Urine Microscopy ... suggestive of nephrotic sydnrome ... ) • Granular Casts ... #Urine #Microscopy ... #nephrology #interpretation
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
Glomerular Diseases ... RBC casts in urine ... severe cases ... diabetes)) #Glomerular ... #Proteinuria #Nephrology
Urinary Casts and Disease Associations
Hyaline - May be nonspecific; seen in normal individuals or during severe
and concentrated urine ... Granular - May ... Muddy-brown" heme-granular ... Fatty - Nephrotic syndrome ... #Differential #Microscopy
Algorithmic Approach to Acute Interstitial Nephritis
When to suspect AIN? (not sensitive)
 • AKI, AKD, rapidly progressive
Algorithmic Approach ... eosinophiluria, microscopic ... tubular proteinuria, granular ... casts/RTE; blend ... #Algorithm #nephrology
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
disease - Alport syndrome ... hematuria syndrome ... hematuria: - RBC casts ... • Nutcracker syndrome ... causes #urology #nephrology
Causes of Proteinuria - Differential Diagnosis Algorithm
Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
• Fanconi's syndrome ... • Drugs Glomerular ... sediment - WBC/RBC casts ... polyangiitis (GPA) / microscopic ... #Proteinuria #Nephrology
Hematuria Workup and Diagnosis Algorithm
 • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
and Diagnosis Algorithm ... unilateral flank pain ... • Evidence of glomerular ... proteinuria, RBC casts ... → Refer to Nephrology
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
Algorithm - Approach ... hemolytic-uremic syndrome ... cell/white cell casts ... of the retina, uveae ... #nephrology