53 results
Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... in sun exposed areas ... hair follicles -> causes ... plugging -> Discoid Rash ... Malar (butterfly) Rash
Top 10 situations when to think about lupus
1) Inflammatory joint pain (especially in the wrists and
to think about lupus ... everywhere) 2) A rash ... pericarditis » is...lupus ... 6) An annular rash ... in photoexposed areas
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Rash - Differential ... Algorithm Pinpoint areas ... Autoimmune Vasculitis (lupus ... Diagnosis #Algorithm #Causes
Crusted Scabies - Physical examination now revealed a generalized erythematous and scaly rash with intense hyperkeratotic
erythematous and scaly rash ... , interdigital areas ... , and genital areas ... Scabies #Microscopy #NEJM
Herpes Zoster Mandibularis - The lesions were scattered along the area that is innervated by the
#Clinical #Photo ... #Mandibularis #Rash ... #NEJM #Shingles
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Drug Induced Lupus ... cases, drug-dependent ... NPSLE rare, Malar rash ... Discontinuation of causal ... Manifestations: Malar rash
Vesiculobullous Skin Rash - Differential Diagnosis Algorithm
Vesicles Fragile/EasiIy Ruptured - Intraepidermal blisters, possibly crusts/erosions
 - Inflammatory
Vesiculobullous Skin Rash ... blisters, possibly crusts ... Bullous systemic lupus ... Diagnosis #Algorithm #causes
Secondary Syphilis Rash
Secondary syphilis is the most contagious of all the stages of this disease, and
Secondary Syphilis Rash ... cavity and genital areas ... , anal or oral areas ... resembling rashes caused ... Diagnosis #Clinical #Photo
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm
Acute Kidney Injury (AKI) - Acute increase
Causes of Acute ... multiple myeloma) • Urate ... IgA, post-strep, lupus ... legionella) • Immune (lupus ... Diagnosis #Algorithm #Causes
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... Manifestations: Malar rash ... , oral ulcers, Lupus ... Positive in 60-80% of cases ... Lupusreference #SLE #lupus