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Uremic Asterixis on Physical Exam

Dr. Arvind Canchi @arvindcanchi

#Uremia #Asterixis #PhysicalExam #clinical #video #neurology #nephrology
Uremic Asterixis ... arvindcanchi #Uremia
AEIOU - Mnemonic of Acute Indications for Dialysis 
A - Acidosis - pH < 7.1
E -
Heart Failure U - Uremia ... - Uremic Pericarditis ... , Uremic Encephalopathy
Indications for Emergent Hemodialysis

Indications: "AEIOU" 
 A - Acidosis ( pH < 7.1 ) 
 E
diuresis U - Uremic ... pericarditis, uremic ... Theophylline U - Uremia
Algorithm for the Treatment of Uremic Pruritus
Nonpharmacologic Treatments:
 • Daily topical emollient
 • Avoidance of extremes
the Treatment of Uremic ... Treatments of Uremic ... 2.5 mcg/d) #Uremic ... #Pruritus #uremia
Gout (Gouty Arthritis) - MSK Radiology
Imaging Findings:
 • Eccentric soft-tissue densities surrounding the third proximal interphalangeal
Gout (Gouty Arthritis ... These are CLASSIC gouty ... • Gouty tophus ... • Gout can present ... Differential diagnosis
Algorithm for workup of thrombocytopenia based on observation of the peripheral blood film. 
TTP/HUS indicates thrombotic
purpura/hemolytic uremic ... #Diagnosis #Differential
Uric Acid Homeostasis
In the liver, purines are metabolized to uric acid. The last step in purine
Uric Acid Homeostasis ... metabolized to uric ... uricase converts uric ... The gout drug pegloticase ... #Homeostasis #Gout
Role of Uric Acid in the Inflammation of Gout

Allopurinol, Febuxostat - Xanthine oxidase
Colchicine - Release of
Role of Uric Acid ... Inflammation of Gout ... inflammation #gout
Gout: Pathogenesis and Clinical Findings
 - Conditions of rapid cell turnover: hemolysis, psoriasis, lymphoproliferative disorders
 -
Gout: Pathogenesis ... , excretion of uric ... into joints -> Uric ... Chronic tophaceous gout ... Complications #Gout
Differential diagnosis of schistocytes / fragmentation hemolysis:
 • Thrombotic microangiopathies (TMA)
    - TTP
Differential diagnosis ... toxin-mediated hemolytic-uremic ... #schistocytes #differential