30 results
Pathophysiology of Tumor Lysis Syndrome (TLS)
Tumor Cell Lysis
-> Release of DNA
 • Purines -> Hypoxanthine /
Lysis Syndrome (TLS ... -> Uric Acid (low ... Urate Nephropathy (low ... urine pH) • Ca-Phos ... Pathophysiology #UricAcid
Hyponatremia Differential Diagnosis Algorithm - Utilizing Uric Acid 
ADH promotes Urea/uric acid excretion along with water
Differential Diagnosis Algorithm ... Osmolarity 2) Urine ... Osmolarity 3) Urine ... Uric Acid - Low ... #uricacid
True Hyponatremia Differential Algorithm

Instead (or in addition) of volume status examination, check urine sodium and serum
Hyponatremia Differential Algorithm ... uric acid: - Urine ... sodium low, uric ... and uric acid low ... #Differential #Algorithm
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting, NGT
Differential Diagnosis Algorithm ... Urine Cl-: Vomiting ... , NGT suction, Low ... (late) • High Urine ... Differential #Diagnosis #Algorithm
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
Differential Diagnosis Algorithm ... Urine Cl-: Vomiting ... , NGT suction, Low ... (late) • High Urine ... Differential #Diagnosis #Algorithm
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine
Urine K+
Algorithm for patients ... EABV, Low Plasma ... • Distal RTA Low-normal ... Plasma HCO3- • Low ... #differential #algorithm
Polyuria - Differential Diagnosis Algorithm
Polyuria = >3L Urine output / 24 hours
Urine osmolality = 2 (Na
Differential Diagnosis Algorithm ... Polyuria = >3L Urine ... output / 24 hours Urine ... nutrition), Azotemia LOW ... Differential #Diagnosis #Algorithm
Volume Based Approach to Hyponatremia
Hypovolemic, Serum uric acid >4
 • Urine Na <20: Extra-renal losses
 •
uric acid >4 • Urine ... Hypothyroidism, Low ... uric acid >4 • Urine ... #Hyponatremia #algorithm ... diagnosis #sodium #low
Hyperuricemia - Differential Diagnosis Algorithm
Primary - Over-production
     • Increased turnover of nucleotides
Primary
Differential Diagnosis Algorithm ... Drug-induced • High purine ... Alcohol #gout #UricAcid ... Differential #Diagnosis #Algorithm
Cushing Syndrome Testing Algorithm
INDICATIONS FOR TESTING:
 • Suspected Cushing syndrome (central obesity, muscle weakness, refractory hypertension)
Testing:
Syndrome Testing Algorithm ... Cortisol, Free Urine ... Cortisol, Saliva • Low ... Serum (or Cortisol Urine ... Syndrome #diagnosis #algorithm